Results 31 to 40 of about 2,546 (253)
Automated Detection of Road Defects Using LSTM and Random Forest
IEEE AccessRoad networks represent an essential factor in economic prosperity and well-being. Assorted damages and defects on the road surface mainly impact the transportation efficiency of road networks and driving safety.
Abdulrahman Alrajhi +3 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
World Electric Vehicle Journal, 2023 The proliferation of autonomous vehicles (AVs) emphasises the pressing need to navigate challenging road networks riddled with anomalies like unapproved speed bumps, potholes, and other hazardous conditions, particularly in low- and middle-income ...
Jibril Abdullahi Bala +2 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Science, 2017 Aviation Clear-air turbulence (CAT), which is invisible to the naked eye and undetectable by sensors onboard aircraft, can cause discomfort or injuries to passengers and often forces planes to alter their flight paths to avoid it. Storer et al. use a global climate model to project how climate warming is expected to influence CAT.
openaire +1 more source
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
Computer Vision-Based Detection and Classification of Road Obstacles: Systematic Literature Review
IEEE AccessRoad obstacles are a major contributor to traffic accidents, making their accurate detection and classification vital for road safety and infrastructure maintenance.
Hamza Assemlali +2 more
doaj +1 more source
Experimental Attempt on Walking Behavior and Stress Assessment in a Completely Darkened Tunnel
Infrastructures, 2021 In case of massive fire incidents in tunnels, ceiling lights are covered by dense smoke, and pedestrians must evacuate in the dark tunnel with almost zero visibility.
Miho Seike +5 more
doaj +1 more source