Results 61 to 70 of about 43,137 (302)

Vibroisolation of railway crossings with the application of shape-memory elements [PDF]

open access: yesTransport Problems, 2009
This research presents existing problem of railway elements and motor –vehicle road elements at their intersections. The objects of simulation research were vehicles passing over a level crossing of automobile road and rail-transportation road. Objective
Jan TARGOSZ
doaj  

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Car Design and Road Crossing Behaviour [PDF]

open access: yes, 2015
Humans possess a highly developed sensitivity for facial features. This sensitivity is also deployed to non-human beings and inanimate objects such as cars. In the present study we aimed to investigate whether car design has a bearing on the behaviour of
Lobmaier, Janek   +3 more
core  

Assessment of pedestrian’s road crossing behaviors and developing a model to predict road crossing speed on zebra‑marked crossings [PDF]

open access: yes, 2022
Zebra marked crosswalk is the most common types of road crossings on urban and rural streets. According to previous stud ies, accidents are frequently occurred on and around marked crosswalk.
Tsige Melese, Damtew   +2 more
core  

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Road crossings change functional diversity and trait composition of stream-dwelling macroinvertebrate assemblages

open access: yesScientific Reports, 2023
Functional diversity is regarded as a key concept in understanding the link between ecosystem function and biodiversity, and is therefore widely investigated in relation to human-induced impacts.
Blanka Gál   +3 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Pedestrians’habits while crossing the road at a former zebra crossing

open access: yesСоциальная психология и общество, 2019
This paper presents research results focused on pedestrians’ crossing behaviour, the role of habit and routine route choice, pedestrians’ perceived safety and comfort, preferences, and waiting times.
Sucha M.
doaj   +1 more source

Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons   +33 more
wiley   +1 more source

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