Results 151 to 160 of about 1,161,829 (246)

Localised Autophagy Inhibition by Nanodiamonds Potentiates Arsenic Therapy With Favourable Safety Profile in Solid Tumours

open access: yesCell Proliferation, EarlyView.
This study presents an NDs‐mediated localised combination strategy that integrates autophagy inhibition with low‐dose ATO sensitization, enabling effective tumour suppression while enhancing safety. NDs‐mediated autophagy blockade enhances ATO efficacy while minimising systemic toxicity, highlighting a promising approach for solid tumour treatment ...
Yiliu Wang   +8 more
wiley   +1 more source

Cryo‐EM structure of GH43 β‐Xylosidase from Enterobacter cloacae provides insights into substrate specificity and the role of an auxiliary domain in enzymatic activity

open access: yesThe FEBS Journal, EarlyView.
Xylan, the second most abundant plant cell wall polysaccharide, is degraded by β‐xylanases and β‐xylosidases. Here, we present the 2.65 Å cryo‐EM structure of Enterobacter cloacae β‐xylosidase (EcXyl43, GH43) and the 2.4 Å X‐ray structure of its inactive F507A mutant.
Lorenzo Briganti   +8 more
wiley   +1 more source

Enhancing ATMO-Street model accuracy through emission source analysis using a dense sensor network: a Warsaw case study. [PDF]

open access: yesEnviron Monit Assess
Sattari A   +5 more
europepmc   +1 more source

The host range paradox of Meloidogyne incognita: a physiological and transcriptomic analysis of nine susceptible interactions across six plant orders

open access: yesNew Phytologist, EarlyView.
Phylogenetic distance of host does not explain phenotypic differences of Meloidogyne incognita parasitism at 25 dpi. Summary The plant–parasitic nematode Meloidogyne incognita is the pathogen with the broadest host range among all known biotrophic interactions.
Victor Hugo Moura de Souza   +11 more
wiley   +1 more source

Effects of Atmospheric CO2 Levels on the Susceptibility of Maize to Diverse Pathogens

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Rising atmospheric CO2 has significant implications for crop productivity and food security. Based on studies in C3 plants, elevated CO2 (eCO2) can shape plant‐pathogen interactions, although the outcomes are often variable. The question of how eCO2 influences immunity and disease development in C4 plants, such as the globally important cereal
Ekkachai Khwanbua   +5 more
wiley   +1 more source

Rising dust pollution across Europe in a changing climate. [PDF]

open access: yesNature
Vasilakos PN   +52 more
europepmc   +1 more source

Understanding extracellular vesicle biology, isolation, and characterization: The theory of EV‐erything

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Extracellular vesicles (EVs), especially exosomes, are nanoparticles increasingly recognized as key regulators of intercellular communication in both physiological and pathological aspects. Despite rapid progress, inconsistencies in nomenclature, isolation, and characterization continue to restrict translational advancement.
Paras Ahmad   +6 more
wiley   +1 more source

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