Results 171 to 180 of about 1,161,829 (246)

A Post–NGP Mitsuokella jalaludinii as a Therapeutic Candidate for Gout

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
Schematic summary of the therapeutic mechanisms and evaluation of the post–NGP strain M. jalaludinii PMC73 for gout. PMC73 demonstrated uric acid–lowering efficacy through purine catabolism and hypoxanthine utilization, along with intracellular uric acid reduction in macrophages.
Mohammed Solayman Hossain, Sukyung Kim, Md Tareque Aziz, Izaz Ahmed, Md Sarower Hossen Shuvo, Hyewon Yang, Yunjeong Jang, Minseo Kim, Seohyeon Jang, Yusol Kim, Soeun Oh, Yunseo Nam, Hoonhee Seo, Ho‐Yeon Song   +13 more
wiley   +1 more source

Vehicle-Road Wear Microplastics: Fragmented Understanding of Their Impacts on Environment. [PDF]

Research (Wash D C)
Hai Y, Yang X, Luan S, Fan Z, He Y, Yang Q, Lu G, Wang C, Wang D, Alberto C.   +9 more
europepmc   +1 more source

A bacterial protein inhibitor of dUTPase disrupts zebrafish embryogenesis through a conserved active‐site mechanism

Protein Science, Volume 35, Issue 10, October 2026.
Abstract Deoxyuridine triphosphatase (dUTPase) is essential for DNA replication fidelity and embryonic development in metazoa, yet whether a protein inhibitor can acutely disrupt dUTPase function in a living vertebrate has not been tested. The Staphylococcus aureus Stl protein inhibits diverse dUTPases in vitro, but its efficacy in a eukaryotic ...
Viktória Perey‐Simon, Zoé Sára Tóth, Dániel Dombovári, Latifa Kazzazy, Máté Varga, Beáta G. Vértessy, Gergely Nándor Nagy, Kinga Nyíri   +7 more
wiley   +1 more source

Occurrence of Potentially Toxic Elements (PTEs) Coupled with Mineralogical and Morphological Characteristics of Residential Indoor Vacuum Dusts from the City of Thessaloniki, Northern Greece. [PDF]

Toxics
Kotsakostoudi C, Bourliva A, Papadopoulou L, Kantiranis N.   +3 more
europepmc   +1 more source

Effects of Trazodone on Testicular Morphology, Sperm Parameters and Contractility of the Distal Cauda Epididymal Duct in Rats

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 4, October 2026.
ABSTRACT Trazodone is an antidepressant approved for the treatment of major depressive disorder and is associated with a low incidence of sexual dysfunction. However, its effects on male reproductive health are not yet fully understood. Therefore, this study aimed to evaluate the effects of repeated trazodone administration on reproductive parameters ...
Maria Santana da Silva, Vitória Barros Marques, Fernanda Karoline Oliveira da Silva, Maele Oliveira de Sena, Yanka do Vale Carvalho, Bruna da Silva Figueiredo, Luana Talinne da Costa Gomes, Samia Ellen Alves Fernandes, Edherlayne Bezerra dos Santos Silva, Jackson Nazareno Gomes de Lima, Anna Karynna Alves de Alencar Rocha, Expedito Silva do Nascimento Junior, Elaine Cristina Gavioli, Edilson Dantas da Silva Junior   +13 more
wiley   +1 more source

Characterization of particulate depositions collected from archeological monuments in Greece and Cyprus using multiple analytical techniques. [PDF]

Environ Sci Pollut Res Int
Gkraikou T, Kozari A, Vouvoudi E, Papadopoulou L, Melfos V, Santarelli B, Samara C.   +6 more
europepmc   +1 more source

Transcriptomic and proteomic signatures underlying nymphal adaptation and foam production in the forage pest Mahanarva spectabilis

Insect Molecular Biology, Volume 35, Issue 5, Page 556-575, October 2026.
RNA‐seq and Batelli gland proteomics of fifth‐instar Mahanarva spectabilis nymphs reveal transcripts and proteins associated with xylem feeding, foam production and environmental interaction. Functional annotation identified genes involved in osmoregulation, detoxification, chemosensation and stress responses, while proteomic analysis confirmed ...
Monique da Silva Bonjour, Angelo José Rinaldi, Eulálio Gutemberg Dias dos Santos, Gabriely Teixeira Bhering Faria, Ana Márcia Escocard de Azevedo Manhães, Jorge Fernando Pereira, Alexander Machado Auad, Maria Goreti de Almeida Oliveira, Humberto Josué de Oliveira Ramos   +8 more
wiley   +1 more source

Changes in air composition driven by differences in biofuel consumption. [PDF]

Environ Sci Pollut Res Int
Farias CN, Pagliuso D, Grandis A, Martins JV, Pereira CR, Guarieiro LLN, Artaxo-Netto PE, Buckeridge MS, de Castro Vasconcellos P.   +8 more
europepmc   +1 more source

PEBP1 Regulates Ferroptosis in Acute Glaucoma: Targeted Therapy Using Engineered Exosomes

The FASEB Journal, Volume 40, Issue 17, 15 September 2026.
General schematic diagram of Spatial and Single‐Cell Transcriptomics Identifies PEBP1 as a Ferroptosis Mediator in Glaucoma: Targeted Intervention by Engineered Stem Cell Exosomes. ABSTRACT Glaucoma is the leading cause of irreversible blindness worldwide, primarily driven by the progressive loss of retinal ganglion cells (RGCs) under pathological high
Yijia Huang, Di Gong, Junhong Guo, Wei Huang, Tingyu Hu, Shengbin Tang, Li Li, Bingkai Feng, Kuanrong Dang, Simin Deng, Yong Liu, Chunyan Tan, Fei Yao, Jiantao Wang   +13 more
wiley   +1 more source

Underground vs outdoor air in the "Wieliczka" Salt Mine health resort: particulate matter and selected gaseous pollutants. [PDF]

Environ Geochem Health
Rogula-Kopiec P, Żurawka M, Bihałowicz JS, Rogula-Kozłowska W, Bralewska K, Smola-Dmochowska A, Kostrzon M, Badyda A.   +7 more
europepmc   +1 more source