Results 51 to 60 of about 175,174 (259)

WeavingUnet: Enhancing dense road extraction by integrating horizontal and vertical features

International Journal of Applied Earth Observations and Geoinformation
Road extraction plays a crucial role in automatically identifying road networks from remote sensing images, which is essential for various applications. However, existing road extraction methods perform poorly when dealing with dense roads.
Xianzhi Ma, Jianhui Li, Mingyang Lv
doaj   +1 more source

Road extraction from high resolution remote sensing image via a deep residual and pyramid pooling network

IET Image Processing, 2021
The road extraction from high resolution remote sensing image is of great importance in a variety of applications. Recently, the abundant deep convolutional neural networks are proposed for road extraction task.
Yibo Han, Pu Han, Manlei Jia
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

WHU-RuR+: A benchmark dataset for global high-resolution rural road extraction

International Journal of Applied Earth Observations and Geoinformation
Efficient and accurate extraction of road networks from high-resolution satellite images is essential for urban planning, construction, and traffic management.
Ningjing Wang, Xinyu Wang, Yang Pan, Wanqiang Yao, Yanfei Zhong   +4 more
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

SWCARE: Switchable learning and connectivity-aware refinement method for multi-city and diverse-scenario road mapping using remote sensing images

International Journal of Applied Earth Observations and Geoinformation
Accurate and efficient mapping of road networks is crucial for evaluating urban development, transportation accessibility, and environmental impact.
Lixian Zhang, Shuai Yuan, Runmin Dong, Juepeng Zheng, Bin Gan, Dengmao Fang, Yang Liu, Haohuan Fu   +7 more
doaj   +1 more source

BrightEarth Roads: Towards Fully Automatic Road Network Extraction from Satellite Imagery

IGARSS 2024 - 2024 IEEE International Geoscience and Remote Sensing Symposium
The modern road network topology comprises intricately designed structures that introduce complexity when automatically reconstructing road networks. While open resources like OpenStreetMap (OSM) offer road networks with well-defined topology, they may not always be up to date worldwide.
Duan, Liuyun, Mapurisa, Willard, Leras, Maxime, Lotter, Leigh, Tarabalka, Yuliya   +4 more
openaire   +3 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Feature Fusion Based Road Extraction for HJ-1-C SAR Image

Leida xuebao, 2014
Road network extraction in SAR images is one of the key tasks of military and civilian technologies. To solve the issues of road extraction of HJ-1-C SAR images, a road extraction algorithm is proposed based on the integration of ratio and directional ...
Lu Ping-ping, Du Kang-ning, Yu Wei-dong, Wang Yu, Deng Yun-kai   +4 more
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source