Results 91 to 100 of about 276,249 (314)

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

Economics of Road Network Ownership [PDF]

open access: yes
This paper seeks to understand the economic impact of centralized and decentralized ownership structures and their corresponding pricing and investment strategies on transportation network performance and social welfare for travelers.
Lei Zhang, David Levinson
core  

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

On-road driving studies to understand why drivers behave as they do at regional rail level crossings

open access: yes, 2013
Improving safety at rail level crossings is an important part of both road and rail safety strategies. While low in number, crashes between vehicles and trains at level crossings are catastrophic events typically involving multiple fatalities and serious
Salmon, P.B.   +12 more
core  

Understanding strategic road network users’ experiences and need – Wave 2 [PDF]

open access: yes, 2014
In 2011, the Government called for an independent review, to assess whether they were taking the right approach to managing, operating and enhancing the Strategic Road Network (SRN), which resulted in the Cook Report ‘A Fresh Start for the Strategic Road
Clay, Daniel   +4 more
core  

Land at Rylston, Sewardstone Road, Waltham Abbey, Essex. Archaeological Evaluation (OASIS ID: heritage1-255159)

open access: yes, 2018
In response to a planning condition on the redevelopment of land at Rylston, Sewardstone Road, Waltham Abbey, Essex, E4 7RG, the Heritage Network was commissioned by ISL Planning Service, acting on behalf of Theori Investments Ltd.
The Heritage Network
core   +1 more source

SP-GEM: Spatial Pattern-Aware Graph Embedding for Matching Multisource Road Networks

open access: yesISPRS International Journal of Geo-Information
Identifying correspondences of road segments in different road networks, namely road-network matching, is an essential task for road network-centric data processing such as data integration of road networks and data quality assessment of crowd-sourced ...
Chenghao Zheng   +8 more
doaj   +1 more source

Online Road Network Understanding

open access: yes, 2023
In this thesis, online understanding of the traffic scene using onboard sensors is addressed. To this end, several approaches for direct extraction of centerline based lane graphs are discussed. Throughout this thesis, the lane graphs are constructed as directed graphs.
openaire   +2 more sources

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

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