Results 81 to 90 of about 8,928,935 (332)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Method for quickly building road network model of open-pit mine based on grid refinement
Meitan xuebaoConstructing the road network in open-pit mining areas is a crucial step for intelligent scheduling and autonomous driving of trucks in these regions. However, given the intricate road conditions, extensive GPS trajectory data from mining vehicles, and ...
Qinghua GU +5 more
doaj +1 more source
The backbone of urban street networks: Degree distribution and connectivity characteristics
Advances in Mechanical Engineering, 2017 This article explores the backbone of urban street networks to reflect the characteristics of the overall network. The model representing the connection of urban road elements based on traffic properties is constructed and then applied to the traffic ...
Wei Zhang +4 more
doaj +1 more source
Synthetic European road freight transport flow data
Data in Brief, 2022 This data article describes a dataset on European road freight traffic. The dataset includes truck traffic flows between 1675 regions all over Europe. In addition to the road freight flows in tons as well as number of vehicles, the dataset also contains ...
Daniel Speth +3 more
doaj +1 more source
Detecting Traffic Conditions Model Based On Clustering Nodes Situations In VANET [PDF]
, 2015 In the last decade, cooperative vehicular network has been one of the most studied areas for developing the intelligent transportation systems (ITS).
Abufanas, A, Peytchev, E
core +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Remote Sensing Road Extraction by Road Segmentation Network
Applied Sciences, 2021 Road extraction from remote sensing images has attracted much attention in geospatial applications. However, the existing methods do not accurately identify the connectivity of the road. The identification of the road pixels may be interfered with by the
Jiahai Tan, Ming Gao, Kai Yang, Tao Duan
doaj +1 more source
Toll roads: a thin end of the wedge? – if only they were [PDF]
, 2012 Nigel Keohane argues that privatising roads could lead to new road construction that would create jobs and bring substantial economic gains from reduced congestion. A politically feasible scheme could also include shared ownership for road users through ‘
Keohane, Nigel
core