Results 61 to 70 of about 215,999 (264)

The backbone of urban street networks: Degree distribution and connectivity characteristics

Advances in Mechanical Engineering, 2017
This article explores the backbone of urban street networks to reflect the characteristics of the overall network. The model representing the connection of urban road elements based on traffic properties is constructed and then applied to the traffic ...
Wei Zhang, Shiguang Wang, Xiujuan Tian, Dexin Yu, Zhaosheng Yang   +4 more
doaj   +1 more source

Remote Sensing Road Extraction by Road Segmentation Network

Applied Sciences, 2021
Road extraction from remote sensing images has attracted much attention in geospatial applications. However, the existing methods do not accurately identify the connectivity of the road. The identification of the road pixels may be interfered with by the
Jiahai Tan, Ming Gao, Kai Yang, Tao Duan
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Template-Based 3D Road Modeling for Generating Large-Scale Virtual Road Network Environment

ISPRS International Journal of Geo-Information, 2019
The 3D road network scene helps to simulate the distribution of road infrastructure and the corresponding traffic conditions. However, the existing road modeling methods have limitations such as inflexibility in different types of road construction ...
Xuequan Zhang, Ming Zhong, Shaobo Liu, Luoheng Zheng, Yumin Chen   +4 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

The searchlight problem for road networks

Theoretical Computer Science, 2015
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Dariusz Dereniowski, Hirotaka Ono 0001, Ichiro Suzuki, Lukasz Wrona, Masafumi Yamashita, Pawel Zylinski   +5 more
openaire   +1 more source

Distributed Short-Term Traffic Flow Prediction Based on Integrating Federated Learning and TCN

IEEE Access
Existing short-term traffic flow prediction methods are based on centralized learning frameworks, which do not consider the diversity of data, leading to limited predictive performance. Additionally, these methods face challenges related to computational
Tongbin Liu, Yong Wang, Hongyu Zhou, Jian Luo, Fangming Deng   +4 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source