Results 61 to 70 of about 1,084,931 (254)

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Effect of pavement surface conditions on road traffic accident - A Review

E3S Web of Conferences, 2022
This study aims to establish an overview of the state-of-the-art relationship between accident risks and pavement surface conditions. The symptoms of pavement surface failure are indicated by roughness, rutting, and skid resistance.
Rahma Mkwata, E. E. Chong
semanticscholar   +1 more source

Self-healing Asphalt for Road Pavements

, 2020
This paper presents a unique self-healing system for asphalt pavement which employs compartmented calcium-alginate fibres encapsulating an asphalt binder healing agent (rejuvenator). This system presents a novel method of incorporating rejuvenators into asphalt pavement mixtures.
Tabakovic, A. (author), Schlangen, E. (author)   +1 more
openaire   +5 more sources

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Analysis of flexible pavement performance prediction models based on structural behaviour

Roads and Bridges, 2019
Sustainable and durable road pavement requires appropriate maintenance and repair strategies. National road authorities collect data describing pavement condition every several years and use specific life-cycle analysis methods to draw up priority plans ...
Paulius Paplauskas, Audrius Vaitkus, Rita Kleizienë   +2 more
doaj   +1 more source

Fire-Retarding Asphalt Pavement for Urban Road Tunnels: A State-of-the-Art Review and Beyond

Fire technology
With the rapid urbanization and development of metropolises, urban road tunnels have been constructed at an increasing rate, significantly alleviating urban traffic pressure, and improving urban resilience.
Xi Jiang, Hehua Zhu, Zhiguo Yan, Fengshou Zhang, Xinyan Huang, Zhen Leng, Chuanqi Yan, Nan Hua, Dong Lu, Xuehui Zhang, Rui Xiao   +10 more
semanticscholar   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Guidelines for the use of accelerated pavement testing data in autonomous vehicle infrastructure research

Journal of Traffic and Transportation Engineering (English ed. Online), 2019
There is much research conducted on the vehicle technologies required for operation of autonomous vehicles (AV) on public roads, as well as analysis of the interaction between AV and the road environment. However, limited research exists on the impact of
Wynand J. vdM. Steyn, James W. Maina
doaj   +1 more source

Detection and Monitoring of Bottom-Up Cracks in Road Pavement Using a Machine-Learning Approach

Algorithms, 2020
The current methods that aim at monitoring the structural health status (SHS) of road pavements allow detecting surface defects and failures. This notwithstanding, there is a lack of methods and systems that are able to identify concealed cracks ...
F. Praticò, R. Fedele, V. Naumov, T. Sauer   +3 more
semanticscholar   +1 more source

Air‐Pressure–Actuated Vibroacoustic Metamaterial With Tunable Bandgap: Design, Modeling, and Characterization

Advanced Engineering Materials, EarlyView.
This article presents the design, modeling, and characterization of air‐pressure–actuated programmable vibroacoustic metamaterials (PVAMM). The study focuses on leveraging air pressure to dynamically tune resonance frequencies for effective noise attenuation.
William Kaal, Michael M. Becker, Sarah C. L. Fischer   +2 more
wiley   +1 more source