Results 21 to 30 of about 207,133 (256)

Road Markings and Signs in Road Safety

open access: yesEncyclopedia, 2022
Due to the dynamic nature and complexity of road traffic, road safety is one of the most demanding social challenges. Therefore, contemporary road safety strategies incorporate a multidisciplinary and comprehensive approaches to address this problem and ...
Darko Babić   +3 more
doaj   +1 more source

Road Safety Analysis of Urban Roads: Case Study of an Italian Municipality

open access: yesSafety, 2018
Attention to the most vulnerable road users has grown rapidly over recent decades. The experience gained reveals an important number of fatalities due to accidents in urban branch roads.
Francesca Demasi   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

open access: yesFEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc   +8 more
wiley   +1 more source

The effects of selected factors on regional road fatalities – analysis of the Łódź region [PDF]

open access: yesMATEC Web of Conferences, 2019
Analysis of regional accident records shows that a country’s national road safety programme does not have the same effect in each of its regions. What may be a serious problem in one region may be of marginal significance in another.
Wachnicka Joanna   +3 more
doaj   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Exploring Patients’ Profiles Associated With the Resolution of Acute Calcium Pyrophosphate Arthritis Treated With Colchicine and Prednisone: Post Hoc Analysis of a Randomized Controlled Trial

open access: yesArthritis Care &Research, EarlyView.
Objective The objective was to identify factors determining acute arthritis resolution and safety with colchicine and prednisone in acute calcium pyrophosphate (CPP) crystal arthritis. Methods We conducted a post hoc analysis of the COLCHICORT trial, which compared colchicine and prednisone for the treatment of acute CPP crystal arthritis, using a ...
Tristan Pascart   +14 more
wiley   +1 more source

Road safety in Africa [PDF]

open access: yesBMJ, 2005
Is part of the broader development process > We must now use every day to act on road safety, and implement effective sustainable action to prevent injury and death on the world's roads. Dr Lee Jong-wook, director-general, World Health Organization T he World Report on Road Traffic Injury Prevention notes that political will and commitment are ...
Meleckidzedeck, Khayesi, Margie, Peden
openaire   +2 more sources

Work-related Road Safety as a Conduit for Community Road Safety

open access: yesJournal of Road Safety, 2010
The aim of this paper is to review the potential of work-related road safety as a conduit for community road safety based on research and practical experience.
Will Murray
doaj  

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