Results 41 to 50 of about 3,308,718 (295)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Strategies to advance road safety in Australia [PDF]
, 2014 As part of a review of the 2011 Australian National Road Safety Strategy research was undertaken to both assess new developments in road safety, including new and improved countermeasures, and to analyse crash and other data to identify any necessary ...
Woolley, J. +4 more
core
MATEC Web of Conferences, 2017 In its bid to become a developed nation in a few years’ time, Malaysia has to consider various prevailing socio-economic and sociotechnical issues in the country.
Mohd Jawi Zulhaidi +5 more
doaj +1 more source
The effects of selected factors on regional road fatalities – analysis of the Łódź region [PDF]
MATEC Web of Conferences, 2019 Analysis of regional accident records shows that a country’s national road safety programme does not have the same effect in each of its regions. What may be a serious problem in one region may be of marginal significance in another.
Wachnicka Joanna +3 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Work-related Road Safety as a Conduit for Community Road Safety
Journal of Road Safety, 2010 The aim of this paper is to review the potential of work-related road safety as a conduit for community road safety based on research and practical experience.
Will Murray
doaj
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
The Material Culture of Road Safety: Road Safety as Museum Display?
Journal of Road Safety, 2009 The museum does not usually spring to mind as a site for road safety promotion but no other institution has so much involvement in collecting and displaying the material culture of motoring and interpreting its history for the general public.
Jennifer Clark
doaj
FEBS Open Bio, EarlyView.Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source