Results 61 to 70 of about 3,308,718 (295)

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem   +9 more
wiley   +1 more source

Policing of road safety in Oman: Perceptions and beliefs of traffic police officers [PDF]

open access: yes, 2015
With increasing motorisation, road safety has become a major concern within Oman. Internationally, traffic policing plays a major role in improving road safety.
Armstrong, Kerry Ann   +3 more
core  

Perceived Impacts and Predictors of Cannabis Products Used by Patients with Rheumatologic Conditions in Alberta, Canada: A Multivariable Analysis of Cross‐Sectional Survey Data

open access: yesArthritis Care &Research, EarlyView.
Objective This study aimed to characterize cannabis product choices (cannabinoid content and formulation) among patients with rheumatologic conditions and their associations with patient factors, patient‐reported perceived side effects, and positive impacts.
Susan Zhang   +10 more
wiley   +1 more source

The influence of safety ownership on occupational road safety outcomes [PDF]

open access: yes, 2010
Questionnaires and interviews were conducted with employees and senior managers from three Australian organisations to explore the relationship between perceived managerial ownership of safety responsibilities and occupational road safety.
Banks, Tamara D.   +5 more
core   +1 more source

Road Accident Data, 1995

open access: yes, 1996
copyright UK Data Service and data collection copyright owner.Road accident statistics are collected from information about personal injury road accidents and their consequent casualties, to a common national standard.
Department of Transport, Road Accident Statistics Branch
core   +4 more sources

Elevated liver enzymes is not an impediment to allopurinol dose escalation: an observational cohort study

open access: yesArthritis Care &Research, Accepted Article.
Objective Routine liver enzyme monitoring is advocated while on allopurinol but supporting guidance is lacking. We assessed the incidence and factors associated with elevated liver enzymes in gout patients commenced on allopurinol. Methods 150 patients with gout and normal baseline serum aminotransferases initiated on allopurinol were followed ...
May Shuen Tang   +4 more
wiley   +1 more source

Incidence and management of cervical spine injuries in fatal road traffic accidents [PDF]

open access: yes, 2009
Cervical spine injuries are common in road trauma and resultant damage can be noted through imaging or replicated in biomechanical studies, all of which have limitations.
Thyer, Elizabeth (R17670)   +5 more
core  

The effects of vehicle restraint systems on road safety [PDF]

open access: yesMATEC Web of Conferences, 2019
Key to understanding the needs and tools of road infrastructure management for preventing runoff-road crashes or minimising their consequences, is to identify the hazards and sources of hazards caused by wrong or improper use of road safety devices and ...
Budzynski Marcin   +8 more
doaj   +1 more source

DigiChrom: A Domain Ontology for Semantic Representation of Trivalent Chromium Platings and Its Large Language Model‐Based Alignment With Multiple Mid‐Level Ontologies

open access: yesAdvanced Engineering Materials, EarlyView.
Digitalizing electroplating requires both domain knowledge and interoperability. This work introduces PlatOn, a domain ontology for trivalent chromium plating and coating characterization, and a hybrid pipeline that aligns it to a mid‐level reference ontology by combining eight similarity metrics with language model reasoning. Expert‐validated mappings
Janik Harter   +10 more
wiley   +1 more source

Road safety benefits of intelligent speed adaptation for Australia [PDF]

open access: yes, 2011
Intelligent Speed Adaptation (ISA) refers to in-vehicle technology systems which assist drivers to keep to or below the speed limit. In 2009-2010 the NSW Centre for Road Safety conducted the NSW ISA Trial which was the largest road safety technology ...
Woolley, J.   +9 more
core  

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