Results 31 to 40 of about 216,325 (261)

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

The Material Culture of Road Safety: Road Safety as Museum Display?

Journal of Road Safety, 2009
The museum does not usually spring to mind as a site for road safety promotion but no other institution has so much involvement in collecting and displaying the material culture of motoring and interpreting its history for the general public.
Jennifer Clark
doaj  

New Deal in Road Safety: Why We Need NGOs

Journal of Road Safety, 2022
Road safety has been receiving increasing global attention, for example: the inclusion of road safety in the 2030 Agenda for Sustainable Development and the United Nations General Assembly (UNGA) adoption of resolution 74/299 “Improving global road ...
Lotte Brondum, Chika Sakashita, Liz Man, Valeria Motta   +3 more
doaj   +1 more source

Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane, Valentina Giunchiglia, Michael C. B. David, Magdalena A. Kolanko, William R. Trender, Peter J. Hellyer, Harmeena Kaur, David J. Sharp, Christopher Carswell, Paresh A. Malhotra, Adam Hampshire   +10 more
wiley   +1 more source

Advocating Global Road Safety

Journal of Road Safety, 2007
The spate of youth road fatalities that we have seen in New South Wales in the last quarter of 2006 represents tragedies that no community should have to bear.
Lori Mooren
doaj  

Identification and Analysis of Problems in the Implementation of Road Safety Audit in Lithuania

The Baltic Journal of Road and Bridge Engineering, 2020
Road Safety Audits have already been tightly incorporated in the road design process throughout the world. It has proven to be an effective way of increasing road safety without requiring many resources.
Aja Tumavičė, Igoris Kravcovas, Vilma Jasiūnienė   +2 more
doaj   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Road Safety for All

Journal of Road Safety, 2016
My daughter, Zenani Zanethemba Mandela was tragically killed two days after celebrating her 13th birthday in a single vehicle drink-driving crash ahead of the 2010 FIFA World Cup in South Africa.
Zoleka Mandela
doaj  

Perceived Impacts and Predictors of Cannabis Products Used by Patients with Rheumatologic Conditions in Alberta, Canada: A Multivariable Analysis of Cross‐Sectional Survey Data

Arthritis Care &Research, EarlyView.
Objective This study aimed to characterize cannabis product choices (cannabinoid content and formulation) among patients with rheumatologic conditions and their associations with patient factors, patient‐reported perceived side effects, and positive impacts.
Susan Zhang, Samuel A.J. Lowe, Frank Sun, Allyson Jones, Tarek Turk, Joanne Olson, Pauline Paul, Shelby Yamamoto, Linda Kolewaski, Elaine Yacyshyn, Cheryl A. Sadowski   +10 more
wiley   +1 more source

Occupational Road Safety 2020: Using PESTELED Analysis to Understand the Work-Related Road Safety Context

Journal of Road Safety, 2011
Since the formation of the coalition government in the UK there has been increasing focus on, and debate about, cuts in the road safety budget. Such cuts will have many knock-on effects for road safety, including the work-related or fleet sector.
Will Murray
doaj