Results 31 to 40 of about 3,477,162 (301)
MATEC Web of Conferences, 2017 In its bid to become a developed nation in a few years’ time, Malaysia has to consider various prevailing socio-economic and sociotechnical issues in the country.
Mohd Jawi Zulhaidi +5 more
doaj +1 more source
Road Traffic Safety Development Trends in Latvia
The Baltic Journal of Road and Bridge Engineering, 2021 The main focus of this article is on the road traffic safety development trends in Latvia. Soon after the regain of independence at the beginning of the 1990s, road traffic safety characteristics in Latvia were the worst in the Latvian history.
Juris Kreicbergs +4 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Strategies to advance road safety in Australia [PDF]
, 2014 As part of a review of the 2011 Australian National Road Safety Strategy research was undertaken to both assess new developments in road safety, including new and improved countermeasures, and to analyse crash and other data to identify any necessary ...
Woolley, J. +4 more
core
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
FEBS Letters, EarlyView.This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Work-related Road Safety as a Conduit for Community Road Safety
Journal of Road Safety, 2010 The aim of this paper is to review the potential of work-related road safety as a conduit for community road safety based on research and practical experience.
Will Murray
doaj
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
The Material Culture of Road Safety: Road Safety as Museum Display?
Journal of Road Safety, 2009 The museum does not usually spring to mind as a site for road safety promotion but no other institution has so much involvement in collecting and displaying the material culture of motoring and interpreting its history for the general public.
Jennifer Clark
doaj
Identification and Analysis of Problems in the Implementation of Road Safety Audit in Lithuania
The Baltic Journal of Road and Bridge Engineering, 2020 Road Safety Audits have already been tightly incorporated in the road design process throughout the world. It has proven to be an effective way of increasing road safety without requiring many resources.
Aja Tumavičė +2 more
doaj +1 more source