Results 71 to 80 of about 96,564 (268)

Toward an integrative framework for local development path analysis

open access: yesEcology and Society, 2018
Despite decades of debate and policy interventions, the wicked social-ecological problem of anthropogenic climate change continues to threaten the sustainability of local communities.
Alastair W. Moore   +3 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

FTF: a quick surveying approach for constructing high resolution digital surface model for road elements

open access: yesGeomatics, Natural Hazards & Risk, 2020
Digital Surface Models (DSMs) are commonly built using data collected via remote sensing techniques such as aerial photogrammetry, LiDAR, and InSAR. DSM accuracy mainly depends upon the type of data used beside the methodology followed.
Abdullah Kamel   +2 more
doaj   +1 more source

High-Road and Low-Road Programs.

open access: yesAI Mag., 1981
Consider a class of computing problem for which all sufficiently short programs are too slow and sufficiently fast programs are too large. Most non-standard problems of this kind were strictly alone for the first twenty-years or so of the computing era. There were two good reasons.
openaire   +3 more sources

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

open access: yesFEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Network Structure, Diversity, and Proactive Resilience Building: a Response to Tompkins and Adger

open access: yesEcology and Society, 2005
Although community social networks can build resilience, and thus, aid adaptation to unexpected environmental change (Tomkins and Adger 2004), not all social networks are created equal.
Lenore Newman, Ann Dale
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Source and distribution of heavy metals in sediment samples from select creeks of the highly urbanized Metro Vancouver Watersheds, Canada

open access: yesDiscover Environment
Forty-seven samples collected from 23 creeks in Metro Vancouver, BC, Canada, were analyzed using X-ray Fluorescence Spectroscopy (XRF) to assess how different land use activities affect physicochemical properties in surface water and metal concentrations
E. K. Gampson   +2 more
doaj   +1 more source

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