Results 71 to 80 of about 284,942 (261)
Current OncologyInterest in AYA cancer care has increased globally over the recent past; however, most of this work disproportionately represents white, heterosexual, middle-income, educated, and able-bodied people.
Tiffany T. Hill +4 more
doaj +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Comprehensive economic development strategy (CEDS) : vision Hampton Roads. [PDF]
The strategy is an economic development planning tool intended to aidlocal governments in decision-making. The document provides an analysisof regional and local economic conditions within the Hampton Roadsregion, defined as including the ten (10) cities
Hampton Roads Partnership
core
Discourse and Writing/RédactologieWe explore relationality and decolonization within the context of our shared attempts to blend Indigenist (Wilson & Hughes, 2019) and Western approaches to information sharing on a redesigned writing centre website.
Theresa Bell +2 more
doaj +1 more source
High-Road and Low-Road Programs.
AI Mag., 1981 Consider a class of computing problem for which all sufficiently short programs are too slow and sufficiently fast programs are too large. Most non-standard problems of this kind were strictly alone for the first twenty-years or so of the computing era. There were two good reasons.
openaire +3 more sources
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Mapping the Complexities of Online Dialogue: An Analytical Modeling Technique
Forum: Qualitative Social Research, 2014 The e-Dialogue platform was developed in 2001 to explore the potential of using the Internet for engaging diverse groups of people and multiple perspectives in substantive dialogue on sustainability.
Robert Newell, Ann Dale
doaj
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Nature-based awe among water professionals and its influence on workplace decision-making
Discover SustainabilityTime spent in nature is restorative for both our physical and mental health. Awe is frequently evoked by nature experiences and increasingly linked to pro-environmental behaviours. Yet, research into awe’s influence on environmental managers specifically
A. Deboer-Smith +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source