Results 61 to 70 of about 96,564 (268)
Evaluation of the Increased Dynamic Effects on the Highway Bridge Superstructure
The Baltic Journal of Road and Bridge Engineering, 2018 Dynamic properties of the bridge superstructure vary depending on many characteristics of the bridge and the loading conditions. In this paper, maximum Dynamic Amplification Factor was calculated for six different types of typical pre-stressed concrete ...
Ilze Paeglite +2 more
doaj +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Mapping the Complexities of Online Dialogue: An Analytical Modeling Technique
Forum: Qualitative Social Research, 2014 The e-Dialogue platform was developed in 2001 to explore the potential of using the Internet for engaging diverse groups of people and multiple perspectives in substantive dialogue on sustainability.
Robert Newell, Ann Dale
doaj
Current OncologyInterest in AYA cancer care has increased globally over the recent past; however, most of this work disproportionately represents white, heterosexual, middle-income, educated, and able-bodied people.
Tiffany T. Hill +4 more
doaj +1 more source
, 2015 Every driver will have experienced the situation in which, as additional traffic joins a road, speeds fall, queues form and travel times become longer and more predictable. Engineers and traffic scientists have devoted considerable effort to understanding how such conditions arise, and how the key parameters of traffic flow, traffic concentration (or ...
May, A, Liu, R, Shepherd, S
openaire +2 more sources
FEBS Open Bio, EarlyView.Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
Nature-based awe among water professionals and its influence on workplace decision-making
Discover SustainabilityTime spent in nature is restorative for both our physical and mental health. Awe is frequently evoked by nature experiences and increasingly linked to pro-environmental behaviours. Yet, research into awe’s influence on environmental managers specifically
A. Deboer-Smith +2 more
doaj +1 more source
Ecological Processes, 2019 Background Agricultural runoff recycling systems are manmade aquatic ecosystems of growing significance to global water sustainability, crop health, and production. This study investigated the seasonal dynamics of microbial community in a three-reservoir
Ping Kong +2 more
doaj +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source