Results 31 to 40 of about 152,386 (299)
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Virtual and Physical Prototyping, 2023 The advents in continuous fibre-reinforced polymer additive manufacturing (CFRP-AM) present unprecedented opportunities for the rapid development of next-generation high-performance composites with selectively and spatially distributed reinforcement ...
Guoquan Zhang +5 more
doaj +1 more source
Journal of Research of the National Bureau of Standards, 1988 In the early sixties, AI researchers attempted to simulate the complicated process of thinking by finding general methods for solving broad classes of problems. This proved too difficult and such attempts failed. In the early seventies the problem was reformulated to include careful attention to data structures but the emphasis was still on general ...
Isenhour, T. L., Marshall, J. C.
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Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Natural Motion for Energy Saving in Robotic and Mechatronic Systems
Applied Sciences, 2019 Energy saving in robotic and mechatronic systems is becoming an evermore important topic in both industry and academia. One strategy to reduce the energy consumption, especially for cyclic tasks, is exploiting natural motion.
Lorenzo Scalera +4 more
doaj +1 more source
IEEE Robotics & Automation Magazine, 2010 We have presented a detailed retrospective on modular robots and discussed connections between modular robots and programmable matter. This field has seen a great deal of creativity and innovation at the level of designing physical systems capable of matching shape to function and algorithms that achieve this capability.
Kyle Gilpin, Daniela Rus
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Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Dynamically Reconfigurable Robotic System
Journal of Robotics and Mechatronics, 1994 This paper deals with experimental aspects of a practical realization method for the cellular robotic system (CEBOT). CEBOT is a dynamically reconfigurable robotic systems which can reconfigure robots in an optimal structure, depending on working purposes and environments This is one of the autonomous distributed, cooperative systems, which are capable
T. Fukuda, S. Nakagawa
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Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source