Results 41 to 50 of about 18,372,646 (292)
Molecular Oncology, EarlyView.This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
wiley +1 more source
Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Molecular Oncology, EarlyView.Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source
Learning‑Based Force‑Sensorless Dual‑Arm Collaborative Manipulation Control
Nanjing Hangkong Hangtian Daxue XuebaoExtreme temperature variations on the lunar surface can cause significant thermal drift in force sensors and render traditional compliant control ineffective.
WU Ruizhe +4 more
doaj +1 more source
A Penetrating-Anchoring Mathematical Model for the Soft Asteroid Anchoring System
International Journal of Aerospace Engineering, 2021 The asteroid landing mechanism is necessary to be anchored to avoid flowing away. At present, the study on the anchoring system is mainly focused on the mechanical design, but there are few researches on the penetrating or anchoring mathematical model ...
Zhijun Zhao, Shuang Wang, Jingdong Zhao
doaj +1 more source
Real-time Doorway Detection and Alignment Determination for Improved Trajectory Generation in Assistive Mobile Robotic Wheelchairs [PDF]
, 2013 Powered wheelchair users may find operation in enclosed environments such as buildings difficult; a fundamental problem exists: wheelchairs are not much narrower than the doorway they wish to pass through.
Howells, Gareth +9 more
core +1 more source
Molecular Oncology, EarlyView.Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis +20 more
wiley +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
Evaluation of Robotic Systems on Cytotoxic Drug Preparation: A Systematic Review and Meta-Analysis
Medicina, 2023 Background and Objectives: With the increased prevalence of patients with cancer, the demand for preparing cytotoxic drugs was increased by health-system pharmacists.
Sangyoon Shin +5 more
doaj +1 more source
A european multicenter study evaluating the flex robotic system in transoral robotic surgery.
, 2017 OBJECTIVES/HYPOTHESIS: To evaluate the application of the Flex Robotic System in transoral robotic surgery (TORS). STUDY DESIGN: Multicenter, prospective, open-label, single-armed clinical study.
Remacle, Marc +19 more
core +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source