Results 61 to 70 of about 18,372,646 (292)

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

open access: yesFEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla   +10 more
wiley   +1 more source

A novel perspective on the regulation of cardiac cell beating: cardiac cell under mechanical stimulation acts as “cell activation button” to activate adjacent cardiac cell

open access: yesJournal of Nanobiotechnology
The regulation of cardiac cell beating is of great significance for understanding cardiac coordination mechanisms and the treatment of cardiovascular diseases.
Zhaotong Chu   +9 more
doaj   +1 more source

A Study of an Agricultural Indoor Robot for Harvesting Edible Bird Nests in Vietnam

open access: yesAgriEngineering
This study demonstrates robot technology for harvesting edible bird’s nests within swiftlet houses. A comprehensive manipulator’s movement analysis of harvesting operation with a separating tool is provided for precisely collecting swiftlet nests.
Duc Anh Vu Trinh, Nguyen Truong Thinh
doaj   +1 more source

Expert systems and robotics

open access: yesJournal of Research of the National Bureau of Standards, 1988
In the early sixties, AI researchers attempted to simulate the complicated process of thinking by finding general methods for solving broad classes of problems. This proved too difficult and such attempts failed. In the early seventies the problem was reformulated to include careful attention to data structures but the emphasis was still on general ...
Isenhour, T. L., Marshall, J. C.
openaire   +1 more source

Beta1 subunits enable fentanyl‐induced BK channel activation and opioid regulation of cerebral artery diameter

open access: yesFEBS Open Bio, EarlyView.
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa   +4 more
wiley   +1 more source

Robotic-assisted internal fixation of femoral fractures [PDF]

open access: yes, 1995
Closed surgical techniques for the internal fixation of femoral fractures require orthopaedic surgeons to work in close proximity to X-rays. In addition to the occupational health risk this imposes, inexperienced surgeons often encounter great difficulty
James R. Hewit (7203329)   +2 more
core   +4 more sources

A nationwide student survey on biochemistry learning resources in Italy

open access: yesFEBS Open Bio, EarlyView.
We conducted a survey among Italian university students to investigate their preferred study materials for biochemistry. We then analyzed the collected data to identify these materials. This information may be valuable to the Biochemistry educational community. The graphical abstract was created with Claude (Opus 5.5; Anthropic, 2026).
Anna Marabotti   +4 more
wiley   +1 more source

Robotic cell transportation system based on micropipette resistance modeling

open access: yesMicrosystems & Nanoengineering
Cell transportation, using a micropipette to pick and place cells from one droplet to another, is a key step in many cell engineering applications. However, most of the current cell transportation operations rely on microscope vision guidance, unsuitable
Qili Zhao   +6 more
doaj   +1 more source

A Faster Fixed-Time Fault Tolerant Sliding Mode Control for Robot Manipulators With Mismatched Disturbances

open access: yesIEEE Access
Mismatched disturbances and actuator failures are primary challenges in the field of robotic manipulators. This research proposes a faster disturbance observer-based fixed-time sliding manifold with accelerated convergence rate developing a comprehensive
Wendong Li   +3 more
doaj   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

open access: yesFEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao   +23 more
wiley   +1 more source

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