Results 71 to 80 of about 158,399 (319)

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Assistive trajectories for human-in-the-loop mobile robotic platforms [PDF]

open access: yes, 2015
Autonomous and semi-autonomous smoothly interruptible trajectories are developed which are highly suitable for application in tele-operated mobile robots, operator on-board military mobile ground platforms, and other mobility assistance platforms.
Howells, Gareth   +5 more
core   +1 more source

Robotic cell transportation system based on micropipette resistance modeling

open access: yesMicrosystems & Nanoengineering
Cell transportation, using a micropipette to pick and place cells from one droplet to another, is a key step in many cell engineering applications. However, most of the current cell transportation operations rely on microscope vision guidance, unsuitable
Qili Zhao   +6 more
doaj   +1 more source

Analysis of the Interaction of Robots as Part of a Robotic System for Biomaterial Aliquotation

open access: yesMachines
The paper considers the problem of interaction between robots with parallel and serial structures that are part of a robotic system for aliquoting biomaterials.
Sergey Khalapyan   +4 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Planning and Real Time Control of a Minimally Invasive Robotic Surgery System

open access: yes, 2009
This paper introduces the planning and control software of a teleoperating robotic system for minimally invasive surgery. It addresses the problem of how to organize a complex system with 41 degrees of freedom including robot setup planning, force ...
Hirzinger, Gerd   +2 more
core  

Workflow of a Preclinical Robotic Magnetic Resonance Imaging-guided Focused Ultrasound Body System

open access: yesJournal of Medical Ultrasound
Background: Establishing an efficient workflow is crucial for the success of magnetic resonance-guided focused ultrasound (MRgFUS) procedures. The current study provides a comprehensive description of the workflow of a customized MRgFUS robotic body ...
Nikolas Evripidou   +6 more
doaj   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

A european multicenter study evaluating the flex robotic system in transoral robotic surgery.

open access: yes, 2017
OBJECTIVES/HYPOTHESIS: To evaluate the application of the Flex Robotic System in transoral robotic surgery (TORS). STUDY DESIGN: Multicenter, prospective, open-label, single-armed clinical study.
Remacle, Marc   +19 more
core   +1 more source

MECANUM-WHEELED ROBOT WITH AI-DRIVEN MANIPULATION

open access: yesCifra: Информационные технологии и телекоммуникации
This study introduces an innovative robotic system that integrates AI vision, a robotic arm, and Mecanum wheels to address challenges in dynamic environments requiring precise navigation and object manipulation.
Mohapatra B.N., Nalge S., Vacche S.
doaj   +1 more source

Home - About - Disclaimer - Privacy