Results 41 to 50 of about 585,201 (269)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Medical robotics: where we come from, where we are and where we could go

open access: yes, 2008
This short note presents a viewpoint about medical ...
Troccaz, Jocelyne
core   +2 more sources

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Do Chatbots Dream of Androids? Prospects for the Technological Development of Artificial Intelligence and Robotics [PDF]

open access: yes, 2019
The article discusses the main trends in the development of artificial intelligence systems and robotics (AI&R). The main question that is considered in this context is whether artificial systems are going to become more and more anthropomorphic, both ...
Efimov, Albert R.
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Acknowledgement to Reviewers of Robotics in 2018

open access: yesRobotics, 2019
Rigorous peer-review is the corner-stone of high-quality academic publishing [...]
Robotics Editorial Office
doaj   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Combining Blockchain and Swarm Robotics to Deploy Surveillance Missions [PDF]

open access: yes, 2019
Current swarm robotics systems are not utilized as frequently in surveillance missions due to the limitations of the existing distributed systems\u27 designs.
Razavi, Ardalan
core   +1 more source

Robot Dream

open access: yes, 2016
In this position paper we present a novel approach to neurobiologically plausible implementation of emotional reactions and behaviors for real-time autonomous robotic systems. The working metaphor we use is the "day" and "night" phases of mammalian life. During the "day" phase a robotic system stores the inbound information and is controlled by a light-
Tchitchigin A.   +3 more
openaire   +4 more sources

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