Results 91 to 100 of about 68,046 (268)

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

UNFOLDING METHODS OF THE CYLINDRICAL SURFACES

open access: yesJournal of Industrial Design and Engineering Graphics, 2017
The aim of this paper is to make a comparison between the classical methods of the descriptive geometry and mathematical methods, for obtain the unfolding of cylinders.
POPA Carmen   +2 more
doaj  

Improvement of high-temperature wear resistance of Zr-based metallic glass by pre-oxidation treatment

open access: yesJournal of Materials Research and Technology
Zr-based bulk metallic glasses (BMGs) are promising for extensive industrial applications due to their superior mechanical properties, excellent glass formation ability (GFA), and low manufacturing costs.
Wenxue Wang   +5 more
doaj   +1 more source

Occlusion-Aware Correlation Particle Filter Target Tracking Based on RGBD Data

open access: yesIEEE Access, 2018
In recent decades, there have been considerable improvements in target-tracking algorithms. However, aspects such as target occlusion, scale variation, and illumination changes still present significant challenges to existing algorithms.
Yayu Zhai   +4 more
doaj   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende   +26 more
wiley   +1 more source

Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick   +19 more
wiley   +1 more source

A Novel Hybrid Stacking Ensemble Classifier for the LegUp Robot Used in Lower Limb Rehabilitation

open access: yesAI
Robust exercise recognition is essential for robot-assisted lower-limb rehabilitation, where misclassifications of sensor-derived movements can degrade therapy execution and supervision.
Anca-Elena Iordan   +9 more
doaj   +1 more source

Modeling and Simulations of Retina-Like Three-Dimensional Computational Ghost Imaging

open access: yesIEEE Photonics Journal, 2019
A retina-like 3-D (three-dimensional) computational ghost imaging (R-3DCGI) is proposed to obtain high resolution while maintaining high imaging efficiency.
Kaiyu Zhang   +5 more
doaj   +1 more source

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall   +16 more
wiley   +1 more source

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