Results 81 to 90 of about 68,046 (268)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

An AI-Based Sensorless Force Feedback in Robot-Assisted Minimally Invasive Surgery

open access: yesInformation
(1) Background: Most robotic MIS platforms lack native haptic feedback, leaving surgeons to infer tissue loads from vision alone—an especially risky limitation in esophageal procedures.
Doina Pisla   +10 more
doaj   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

A Soft, Centimeter‐Scaled, Thin‐Cable‐Crawling Robot for Narrow Space Inspection

open access: yesAdvanced Intelligent Systems
Cables are critical in engineering structures for load‐bearing, electronic connection, and mechanical transmission. Various cable‐crawling robots (CCRs) have been developed to perform scheduled inspection or convey supplies.
Wentao Ma   +5 more
doaj   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Robotics [PDF]

open access: yesHMD Praxis der Wirtschaftsinformatik, 2020
Sara D'Onofrio, Stefan Meinhardt
openaire   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Colorful 3D Reconstruction and an Extended Depth of Field for a Monocular Biological Microscope Using an Electrically Tunable Lens

open access: yesBiomimetics
This paper presents a monocular biological microscope with colorful 3D reconstruction and an extended depth of field using an electrically tunable lens. It is based on a 4f optical system with an electrically tunable lens at the confocal plane. Rapid and
Yang Cheng   +4 more
doaj   +1 more source

Intelligent Positioning for a Commercial Mobile Platform in Seamless Indoor/Outdoor Scenes based on Multi-sensor Fusion

open access: yesSensors, 2019
Many traffic occasions such as tunnels, subway stations and underground parking require accurate and continuous positioning. Navigation and timing services offered by the Global Navigation Satellite System (GNSS) is the most popular outdoor positioning ...
Dongsheng Wang   +3 more
doaj   +1 more source

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