Results 71 to 80 of about 68,046 (268)

A Novel De-Noising Method for Improving the Performance of Full-Waveform LiDAR Using Differential Optical Path

open access: yesRemote Sensing, 2017
A novel de-noising method for improving the performance of full-waveform light detection and ranging (LiDAR) based on differential optical path is proposed, and the mathematical models of this method are developed and verified.
Yang Cheng   +7 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Multi-scale deep learning and clustering-based tabletop object instance segmentation for robot manipulation

open access: yesInternational Journal of Advanced Robotic Systems
3D object instance segmentation plays a vital role in various applications such as autonomous driving, robotics and virtual reality. However, tabletop scenes exhibit diverse object complexities and size variations.
Zhihong Jiang   +4 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Robots with language [PDF]

open access: yesFrontiers in Neurorobotics, 2010
Trying to understand human language by constructing robots that have language necessarily implies an embodied view of language, where the meaning of linguistic expressions is derived from the physical interactions of the organism with the environment. The paper describes a neural model of language according to which the robot's behaviour is controlled ...
openaire   +5 more sources

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Construction robotics

open access: yesAutonomous Robots, 2006
[abstFig src='/00280002/01.jpg' width=""300"" text='A humanoid robot riding an excavator' ]The following article reviews past and current tendencies and derives and describes opportunities for construction robotics and automation. There substantial evidence in the construction industry, that conventional construction methodology has reached its limits.
openaire   +1 more source

Co-Robots as Care Robots

open access: yesCoRR, 2020
Accepted paper of the AAAI 2020 Spring Symposium "Applied AI in Healthcare: Safety, Community, and the Environment" (Stanford University).
openaire   +2 more sources

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

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