Results 51 to 60 of about 68,046 (268)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
IVO Robot: A New Social Robot for Human-Robot Collaboration
2022 17th ACM/IEEE International Conference on Human-Robot Interaction (HRI), 2022 © 2022 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes,creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component ...
Laplaza Galindo, Javier +7 more
openaire +3 more sources
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
LubricantsThe mechanical and tribological behavior of eccentric bearings is crucial for the performance of a RV reducer. By combining the finite element model (FEM) and the elastohydrodynamic lubrication (EHL) method, a comprehensive model for the cylindrical ...
Xinyue Zhang +4 more
doaj +1 more source
International Journal of Smart and Nano Materials, 2022 Ionic polymer-metal composites (IPMCs) are typical smart materials that are commonly used in bionic applications, including soft robots, bionic flapping aircraft, and bionic fish.
Zicai Zhu +4 more
doaj +1 more source
Communications of the ACM, 2017 Healthcare robotics can provide health and wellness support to billions of people.
openaire +3 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Locomoting Robots Composed of Immobile Robots [PDF]
2018 Second IEEE International Conference on Robotic Computing (IRC), 2018 Robotic materials are multi-robot systems formulated to leverage the low-order computation and actuation of the constituents to manipulate the high-order behavior of the entire material. We study the behaviors of ensembles composed of smart active particles, smarticles.
Ross Warkentin +2 more
openaire +2 more sources
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Hanjie xuebaoTo improve the mechanical properties of aluminum alloy and steel joints and suppress the excessive formation of brittle intermetallic compounds (IMCs) at the interface during laser welding, AlSiCu alloy powder and composite powder prepared by AlSiCu + Mo
Min LEI +6 more
doaj +1 more source