Results 71 to 80 of about 23,058 (312)

Farm robots: ecological utopia or dystopia?

, 2021
Farm robots may lead to an ecological utopia where swarms of small robots help in overcoming the yield penalties and labor requirements associated with agroecological farming – or a dystopia with large robots cultivating monocultures.
Daum, Thomas,
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Functional Modeling for Monitoring of Robotic System

Applied Artificial Intelligence, 2018
With the expansion of robotic applications in the industrial domain, it is important that the robots can execute their tasks in a safe and reliable way.
Haiyan Wu, Rikke Bateman, Xinxin Zhang, Morten Lind   +3 more
doaj   +1 more source

A Perceptual Memory System for Affordance Learning in Humanoid Robots

, 2011
Kammer M, Tscherepanow M, Schack T, Nagai Y. A Perceptual Memory System for Affordance Learning in Humanoid Robots. In: Honkela T, Duch W, Girolami M, Kaski S, eds.
Nagai, Yukie, Honkela, Timo, Marko Tscherepanow, Tscherepanow, Marko, Duch, Wlodzislaw, Kaski, Samuel, Marc Kammer, Yukie Nagai, Thomas Schack, Kammer, Marc, Girolami, Mark, Schack, Thomas   +11 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

The Role of the Robot Mass and Velocity in Physical Human-Robot Interaction - Part II: Constrained Blunt Impacts

, 2008
Accidents occurring with classical industrial robots often lead to fatal injuries. Presumably, this is to a great extent caused by the possibility of clamping the human in the confined workspace of the robot.
Hirzinger, Gerd, Albu-Schäffer, Alin Olimpiu, Haddadin, Sami, Alin Albu-Schaffer, Frommberger, Mirko, Gerd Hirzinger, Sami Haddadin, Mirko Frommberger   +7 more
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Action recognition: From static datasets to moving robots

, 2017
Deep learning models have achieved state-of-the- art performance in recognizing human activities, but often rely on utilizing background cues present in typical computer vision datasets that predominantly have a stationary camera.
Shirazi, Sareh, Sareh Shirazi, Upcroft, Ben, Milford, Michael, Michael Milford, Rezazadegan, Fahimeh, Ben Upcrofit, Fahimeh Rezazadegan   +7 more
core   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Things Are Made for What They Are: Solving Manipulation Tasks by Using Functional Object Classes

, 2012
Solving arbitrary manipulation tasks is a key feature for humanoid service robots. However, especially when tasks involve handling complex mechanisms or using tools, a generic action description is hard to define.
Hirzinger, Gerd, Leidner, Daniel, Christoph Borst, Gerd Hirzinger, Borst, Christoph, Daniel Leidner   +5 more
core   +1 more source