Results 51 to 60 of about 148,807,208 (269)
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
On the Passivity Based Impedance Control of Flexible Joint Robots [PDF]
, 2008 In this paper, a novel type of impedance controllers for flexible joint robots is proposed. As a target impedance, a desired stiffness and damping are considered without inertia shaping.
Hirzinger, Gerd +5 more
core +1 more source
IEEE AccessOver the past few years, breakthroughs in deep learning applied to computer vision has driven the development of novel techniques and various solutions for automatic license plate recognition (ALPR).
Amir Ismail +3 more
doaj +1 more source
Child-Robot Conversation in the Wild Wild Home: A Language Processing User Study
2023 32nd IEEE International Conference on Robot and Human Interactive Communication (RO-MAN), 2023 Abstract—Child-robot interaction (CRI) has been mostly studied in labs and classroom settings. In this work, we share a CRI language processing study carried out in children’s homes. Any automated system deployed “in-the-wild” faces practical problems, but when the target users are children, these problems get even more sensitive and challenging.
Guillermo Pérez 0001 +10 more
openaire +3 more sources
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
The Convergence of AI and animal-inspired robots for ecological conservation
Ecological InformaticsAugmenting artificial intelligence through the integration of animal-inspired robots holds immense promise for transforming the landscape of ecological conservation.
Naqash Afzal +3 more
doaj +1 more source
Facial Micro-Expression Recognition Using Two-Dimensional Landmark Feature Maps
IEEE Access, 2020 Emotion recognition based on facial expressions is very important for effective interaction of humans with artificial intelligence (AI) systems such as social robots.
Dong Yoon Choi, Byung Cheol Song
doaj +1 more source
FEBS Open Bio, EarlyView.The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source