Results 101 to 110 of about 3,179,683 (287)
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
A Novel Evolutionary Algorithm for Designing Robust Analog Filters
Algorithms, 2018 Designing robust circuits that withstand environmental perturbation and device degradation is critical for many applications. Traditional robust circuit design is mainly done by tuning parameters to improve system robustness.
Shaobo Li, Wang Zou, Jianjun Hu
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Robust Optimal Design of SPMSM Considering Manufacturing Tolerances of Permanent Magnets
IEEE AccessServo motors are widely used in systems that require high speed, high precision, and accurate position control. One of the critical aspects of servo motor design is the minimization of cogging torque to reduce motor vibration and noise.
Jae-Hyeon Yeo, Jun-Kyu Kang, Jin Hur
doaj +1 more source
Development of an experiment-based robust design paradigm for multiple quality characteristics using physical programming [PDF]
, 2007 The well-known quality improvement methodology, robust design, is a powerful and cost-effective technique for building quality into the design of products and processes.
Antony, Jiju +2 more
core +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
A New Nozzle for Continuous Inkjet Printers
Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2010 The shape of a nozzle for high-quality printing was optimized by using a standard, robust design method, and a method for fabricating the optimized nozzle was established.
Mamoru OKANO +4 more
doaj +1 more source
Sensitivity analysis modelling for microscale multiphysics robust engineering design [PDF]
, 2007 Sensitivity Analysis (SA) plays an important role in the development of any practical engineering model. It can help to reveal the sources and mechanisms of variability that provide the key to understanding system uncertainty.
Atherton, MA +4 more
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