Results 101 to 110 of about 3,261,710 (304)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Desirability-Based Multi-Response Robust Design Optimization of IPMSM Considering Manufacturing Uncertainty

open access: yesIEEE Access
Manufacturing uncertainties such as variations in material properties, dimensional tolerances, and assembly deviations of permanent magnets (PMs) significantly affect the mean and variance of key motor performances, including back electromotive force ...
Sang-Ryul Jeon, Kyu-Seob Kim
doaj   +1 more source

Multi-Objective Design Optimization of a Hexa-Rotor With Disturbance Rejection Capability Using an Evolutionary Algorithm

open access: yesIEEE Access, 2018
In this paper, a methodology to design a hexa-rotor with the capability to reject disturbances using tilted propellers is presented. The methodology proposes the use of a robustness index as a measurement of the capability to reject external disturbances.
Victor Manuel Arellano-Quintana   +2 more
doaj   +1 more source

Analysis-of-marginal-Tail-Means (ATM): a robust method for discrete black-box optimization

open access: yes, 2018
We present a new method, called Analysis-of-marginal-Tail-Means (ATM), for effective robust optimization of discrete black-box problems. ATM has important applications to many real-world engineering problems (e.g., manufacturing optimization, product ...
Mak, Simon, Wu, C. F. Jeff
core   +2 more sources

Robust multivariable feedback design

open access: yesInternational Journal of Control, 1989
A primary role of feedback design is to enable a system to cope with the inevitable uncertainly associated with its description. Although it is often the case that we have at hand a practical description of both the size and structure of the expected uncertainty, simple multivariable design strategies which effectively incorporate this information have
Kouvaritakis, B, Trimboli, M
openaire   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Robust Design for the Lower Extremity Exoskeleton Under a Stochastic Terrain by Mimicking Wolf Pack Behaviors

open access: yesIEEE Access, 2018
While kinematics analysis plays an important role in studying human limb motions, existing methods (namely, direct and inverse kinematics) have their deficiencies.
Zhonglai Wang   +3 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

ARLE GPS: a tool to support architects in the computer-aided design of spatial planning and generation of house designs

open access: yesDesign Science
The ARLE GPS tool provides computer-aided design support for solving problems with the spatial planning and design of houses, using a robust design model with physical-biological and cost strategies. This enables architects to eliminate uncertainties and
Daniel das Neves Martins
doaj   +1 more source

Sampling-based Learning Control for Quantum Systems with Uncertainties

open access: yes, 2015
Robust control design for quantum systems has been recognized as a key task in the development of practical quantum technology. In this paper, we present a systematic numerical methodology of sampling-based learning control (SLC) for control design of ...
Chen, Chunlin   +5 more
core   +1 more source

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