Results 71 to 80 of about 3,216,313 (259)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Energies, 2019 Power transmission and protection of power electronics−electromagnetic actuators are crucial parts in renewable energy systems (energy management of photovoltaic, wind power, hybrid and electric vehicles).
Jie Deng, Xiaohan Liu, Guofu Zhai
doaj +1 more source
Robust Lattice Alignment for K-user MIMO Interference Channels with Imperfect Channel Knowledge
, 2011 In this paper, we consider a robust lattice alignment design for K-user quasi-static MIMO interference channels with imperfect channel knowledge. With random Gaussian inputs, the conventional interference alignment (IA) method has the feasibility problem
Du, Yinggang +3 more
core +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Robust Topology Optimization for Compliant Mechanisms Considering Uncertainty of Applied Loads
Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2008 In this study, a robust topology optimization method is proposed for compliant mechanisms, where the effect that variation of the input load direction has on the output displacement is considered.
Nozomu KOGISO +4 more
doaj +1 more source
Design and fabrication of chemically robust three-dimensional microfluidic valves [PDF]
, 2007 A current problem in microfluidics is that poly(dimethylsiloxane) (PDMS), used to fabricate many microfluidic devices, is not compatible with most organic solvents. Fluorinated compounds are more chemically robust than PDMS but, historically, it has been
Chen, Yan +7 more
core +2 more sources
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Robust Design of Suspension System with Polynomial Chaos Expansion and Machine Learning
Наука и техника, 2020 During the early development of a new vehicle project, the uncertainty of parameters should be taken into consideration because the design may be perturbed due to real components’ complexity and manufacturing tolerances. Thus, the numerical validation of
H. Gao +3 more
doaj +1 more source
On the design of Robust tube-based MPC for tracking [PDF]
, 2008 17th IFAC World Congress (IFAC'08)Seoul, Korea, July 6-11This paper deals with the design procedure of the recently presented robust MPC for tracking of constrained linear systems with additive disturbances.
Alamo, Teodoro +3 more
core +1 more source