Results 81 to 90 of about 2,041,920 (276)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Robustness of Device Independent Dimension Witnesses
, 2012 Device independent dimension witnesses provide a lower bound on the dimensionality of classical and quantum systems in a "black box" scenario where only correlations between preparations, measurements and outcomes are considered.
Antonio Acín +5 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Performance Assessment of a Model-based DC Motor Scheme
Applications of Modelling and Simulation, 2019 The separately-excited DC motor is a high-performance variable speed drive with industrial applications such as in robotics, actuation, control and guided manipulation due to its precision, simplicity, continuous control feature and wide speed range ...
Ihechiluru S. Okoro, Clinton O. Enwerem
doaj
Portfolio Implementation Risk Management Using Evolutionary Multiobjective Optimization
Applied Sciences, 2017 Portfolio management based on mean-variance portfolio optimization is subject to different sources of uncertainty. In addition to those related to the quality of parameter estimates used in the optimization process, investors face a portfolio ...
David Quintana +3 more
doaj +1 more source
Developmental Evolution: Getting Robust About Robustness [PDF]
Current Biology, 2002 In the context of development, a process is robust if it can proceed normally despite the enormous capacity for perturbation inherent in all biological systems. A new mode of theoretical modeling of genetic networks holds great promise for increasing our understanding of both the quantitative mechanisms of robustness and its evolutionary impact.
openaire +3 more sources
SWEEPFINDER2: Increased sensitivity, robustness, and flexibility
, 2015 SweepFinder is a popular program that implements a powerful likelihood-based method for detecting recent positive selection, or selective sweeps. Here, we present SweepFinder2, an extension of SweepFinder with increased sensitivity and robustness to the ...
DeGiorgio, Michael +4 more
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Journal of the Brazilian Chemical Society, 2003 The analytical performance of axially and radially viewed inductively coupled plasma optical emission spectrometers (AX-ICP OES and RD-ICP OES, respectively) were evaluated in terms of the Mg II/Mg I ratio, matrix effects, and detection limits (LOD). All
Silva Júlio C. J. +2 more
doaj
Research of PMSM-DTC system based on the super-twisting second sliding mode control
Journal of Hebei University of Science and Technology, 2017 Aiming at the problems that the conventional permanent magnet synchronous motor direct torque control system (PMSM-DTC) is susceptible to the influence of parameter change and torque ripple, it is proposed that the space voltage vector modulation ...
Suying ZHANG +4 more
doaj +1 more source