Results 91 to 100 of about 567,669 (271)
Co-evolution, Determinism and Robustness
, 1999 Robustness has long been recognised as a critical issue for coevolutionary learning. It has been achieved in a number of cases, though usually in domains which involve some form of non-determinism. We examine a deterministic domain - a pseudo real-time two-player game called Tron - and evolve a neural network player using a simple hill-climbing ...
A.D. Blair, Elizabeth Sklar, P. Funes
openaire +1 more source
Robustness of Phylogenetic Inference Based on Minimum Evolution
Bulletin of Mathematical Biology, 2010 Minimum evolution is the guiding principle of an important class of distance-based phylogeny reconstruction methods, including neighbor-joining (NJ), which is the most cited tree inference algorithm to date. The minimum evolution principle involves searching for the tree with minimum length, where the length is estimated using various least-squares ...
Pardi, Fabio +2 more
openaire +4 more sources
Nonlinear Schrodinger equation with chaotic, random, and nonperiodic nonlinearity
, 2009 In this paper we deal with a nonlinear Schr\"{o}dinger equation with chaotic, random, and nonperiodic cubic nonlinearity. Our goal is to study the soliton evolution, with the strength of the nonlinearity perturbed in the space and time coordinates and to
Avelar, A. T. +4 more
core +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
A direct experimental test of Ohno’s hypothesis
eLifeGene duplication drives evolution by providing raw material for proteins with novel functions. An influential hypothesis by Ohno (1970) posits that gene duplication helps genes tolerate new mutations and thus facilitates the evolution of new phenotypes ...
Ljiljana Mihajlovic +7 more
doaj +1 more source
Electronic Journal of Qualitative Theory of Differential Equations, 2011 In this paper, we study periodic boundary value problems for a class of linear fractional evolution equations involving the Caputo fractional derivative.
JinRong Wang, Yong Zhou, Michal Fečkan
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
Impact of translational error‐induced and error‐free misfolding on the rate of protein evolution
Molecular Systems Biology, 2010 What determines the rate of protein evolution is a fundamental question in biology. Recent genomic studies revealed a surprisingly strong anticorrelation between the expression level of a protein and its rate of sequence evolution.
Jian‐Rong Yang +2 more
doaj +1 more source
Research on a Dynamic Virus Propagation Model to Improve Smart Campus Security
IEEE Access, 2018 This paper focuses on the security and robustness of smart campuses by studying a virus propagation model. Establishing a model that reflects the epidemiological transmission mechanism is a primary method for studying disease outbreaks and control ...
Lei Wang +3 more
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