Results 21 to 30 of about 3,019,839 (180)
EvoRSR: an integrated system for exploring evolution of RNA structural robustness
BMC Bioinformatics, 2009 Background Robustness, maintaining a constant phenotype despite perturbations, is a fundamental property of biological systems that is incorporated at various levels of biological complexity.
Ni Ming +4 more
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Effects of ploidy and recombination on evolution of robustness in a model of the segment polarity network. [PDF]
PLoS Computational Biology, 2009 Many genetic networks are astonishingly robust to quantitative variation, allowing these networks to continue functioning in the face of mutation and environmental perturbation. However, the evolution of such robustness remains poorly understood for real
Kerry J Kim, Vilaiwan M Fernandes
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Evolution favors protein mutational robustness in sufficiently large populations
BMC Biology, 2007 Background An important question is whether evolution favors properties such as mutational robustness or evolvability that do not directly benefit any individual, but can influence the course of future evolution.
Venturelli Ophelia S +5 more
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Evolution of dominance in gene expression pattern associated with phenotypic robustness
BMC Ecology and Evolution, 2021 Background Mendelian inheritance is a fundamental law of genetics. When we consider two genomes in a diploid cell, a heterozygote’s phenotype is dominated by a particular homozygote according to the law of dominance.
Kenji Okubo, Kunihiko Kaneko
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, 2022 This report summarizes how to systematically analyze a software architecture with respect to a quality attribute requirement for robustness. The report introduces the quality attribute of robustness and common forms of robustness requirements for ...
Philip Bianco (3891784) +3 more
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Upstream plasticity and downstream robustness in evolution of molecular networks
BMC Evolutionary Biology, 2004 Background Gene duplication followed by the functional divergence of the resulting pair of paralogous proteins is a major force shaping molecular networks in living organisms.
Eriksen Kasper +3 more
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Determinative developmental cell lineages are robust to cell deaths. [PDF]
PLoS Genetics, 2014 All forms of life are confronted with environmental and genetic perturbations, making phenotypic robustness an important characteristic of life. Although development has long been viewed as a key component of phenotypic robustness, the underlying ...
Jian-Rong Yang +2 more
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Non-Darwinian Molecular Biology
Frontiers in Genetics, 2022 With the discovery of the double helical structure of DNA, a shift occurred in how biologists investigated questions surrounding cellular processes, such as protein synthesis. Instead of viewing biological activity through the lens of chemical reactions,
Alexander F. Palazzo, Nevraj S. Kejiou
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The evolution of genome compression and genomic novelty in RNA viruses [PDF]
, 2007 The genomes of RNA viruses are characterized by their extremely small size and extremely high mutation rates ( typically 10 kb and 10(-4)/ base/ replication cycle, respectively), traits that are thought to be causally linked.
Rambaut, Andrew +2 more
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The robustness of a signaling complex to domain rearrangements facilitates network evolution. [PDF]
PLoS Biology, 2014 The rearrangement of protein domains is known to have key roles in the evolution of signaling networks and, consequently, is a major tool used to synthetically rewire networks.
Paloma M Sato +3 more
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