Results 41 to 50 of about 548,676 (308)

Quantum computing of delocalization in small-world networks [PDF]

open access: yes, 2005
We study a quantum small-world network with disorder and show that the system exhibits a delocalization transition. A quantum algorithm is built up which simulates the evolution operator of the model in a polynomial number of gates for exponential number
B. Georgeot   +5 more
core   +3 more sources

Upstream plasticity and downstream robustness in evolution of molecular networks

open access: yesBMC Evolutionary Biology, 2004
Background Gene duplication followed by the functional divergence of the resulting pair of paralogous proteins is a major force shaping molecular networks in living organisms.
Eriksen Kasper   +3 more
doaj   +1 more source

Evolution of dominance in gene expression pattern associated with phenotypic robustness

open access: yesBMC Ecology and Evolution, 2021
Background Mendelian inheritance is a fundamental law of genetics. When we consider two genomes in a diploid cell, a heterozygote’s phenotype is dominated by a particular homozygote according to the law of dominance.
Kenji Okubo, Kunihiko Kaneko
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

On the Interplay between the Evolvability and Network Robustness in an Evolutionary Biological Network: A Systems Biology Approach

open access: yesEvolutionary Bioinformatics, 2011
In the evolutionary process, the random transmission and mutation of genes provide biological diversities for natural selection. In order to preserve functional phenotypes between generations, gene networks need to evolve robustly under the influence of ...
Bor-Sen Chen, Ying-Po Lin
doaj   +1 more source

Highly Optimized Tolerance: Robustness and Design in Complex Systems [PDF]

open access: yes, 2000
Highly optimized tolerance (HOT) is a mechanism that relates evolving structure to power laws in interconnected systems. HOT systems arise where design and evolution create complex systems sharing common features, including (1) high efficiency ...
Carlson, J. M., Doyle, John
core   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

open access: yesFEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur   +5 more
wiley   +1 more source

Environmental noise, genetic diversity and the evolution of evolvability and robustness in model gene networks. [PDF]

open access: yesPLoS ONE, 2012
The ability of organisms to adapt and persist in the face of environmental change is accepted as a fundamental feature of natural systems. More contentious is whether the capacity of organisms to adapt (or "evolvability") can itself evolve and the ...
Christopher F Steiner
doaj   +1 more source

Observation of a localized flat-band state in a photonic Lieb lattice [PDF]

open access: yes, 2015
We show experimentally how a non-diffracting state can be excited in a photonic Lieb lattice. This lattice supports three energy bands, including a perfectly flat middle band, which corresponds to an infinite effective mass with zero dispersion.
Andersson, Erika   +6 more
core   +2 more sources

Neutral Evolution of Robustness in Drosophila microRNA Precursors [PDF]

open access: yesMolecular Biology and Evolution, 2011
Mutational robustness describes the extent to which a phenotype remains unchanged in the face of mutations. Theory predicts that the strength of direct selection for mutational robustness is at most the magnitude of the rate of deleterious mutation. As far as nucleic acid sequences are concerned, only long sequences in organisms with high deleterious ...
Price, N   +4 more
openaire   +2 more sources

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