Results 41 to 50 of about 562,963 (309)

Degeneracy: a design principle for achieving robustness and evolvability

open access: yes, 2009
Robustness, the insensitivity of some of a biological system's functionalities to a set of distinct conditions, is intimately linked to fitness. Recent studies suggest that it may also play a vital role in enabling the evolution of species.
Bender, Axel, Whitacre, James M
core   +1 more source

Environmental noise, genetic diversity and the evolution of evolvability and robustness in model gene networks. [PDF]

open access: yesPLoS ONE, 2012
The ability of organisms to adapt and persist in the face of environmental change is accepted as a fundamental feature of natural systems. More contentious is whether the capacity of organisms to adapt (or "evolvability") can itself evolve and the ...
Christopher F Steiner
doaj   +1 more source

Highly Optimized Tolerance: Robustness and Design in Complex Systems [PDF]

open access: yes, 2000
Highly optimized tolerance (HOT) is a mechanism that relates evolving structure to power laws in interconnected systems. HOT systems arise where design and evolution create complex systems sharing common features, including (1) high efficiency ...
Carlson, J. M., Doyle, John
core   +1 more source

Stereotactic Body Radiation Therapy for Pediatric, Adolescent, and Young Adult Patients With Osteosarcoma: Local Control Outcomes With Dosimetric Analysis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Osteosarcoma is a radioresistant tumor that may benefit from stereotactic body radiation therapy (SBRT) for locoregional control in metastatic/recurrent disease. We report institutional practice patterns, outcomes, toxicity, and failures in osteosarcoma patients treated with SBRT.
Jenna Kocsis   +13 more
wiley   +1 more source

Neutral Evolution of Robustness in Drosophila microRNA Precursors [PDF]

open access: yesMolecular Biology and Evolution, 2011
Mutational robustness describes the extent to which a phenotype remains unchanged in the face of mutations. Theory predicts that the strength of direct selection for mutational robustness is at most the magnitude of the rate of deleterious mutation. As far as nucleic acid sequences are concerned, only long sequences in organisms with high deleterious ...
Price, N   +4 more
openaire   +2 more sources

Non-Darwinian Molecular Biology

open access: yesFrontiers in Genetics, 2022
With the discovery of the double helical structure of DNA, a shift occurred in how biologists investigated questions surrounding cellular processes, such as protein synthesis. Instead of viewing biological activity through the lens of chemical reactions,
Alexander F. Palazzo, Nevraj S. Kejiou
doaj   +1 more source

Observation of a localized flat-band state in a photonic Lieb lattice [PDF]

open access: yes, 2015
We show experimentally how a non-diffracting state can be excited in a photonic Lieb lattice. This lattice supports three energy bands, including a perfectly flat middle band, which corresponds to an infinite effective mass with zero dispersion.
Andersson, Erika   +6 more
core   +2 more sources

Changes in Body Composition in Children and Young People Undergoing Treatment for Acute Lymphoblastic Leukemia: A Systematic Review and Meta‐Analysis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Ongoing evidence indicates increased risk of sarcopenic obesity among children and young people (CYP) with acute lymphoblastic leukemia (ALL), often beginning early in treatment, persisting into survivorship. This review evaluates current literature on body composition in CYP with ALL during and after treatment.
Lina A. Zahed   +5 more
wiley   +1 more source

Robust and simple database evolution

open access: yesInformation Systems Frontiers, 2017
This is the artifact for the paper titled "POKER: Permutation-based SIMD Execution of Intensive Tree Search by Path Encoding" accepted at CGO 2018. This artifact helps reproduce the results presented in Figures 7 - 9 and Tables 2 - 3 in Section 4. For more information on how to use it, please refer to our paper and the README.txt file in this package ...
Herrmann, Kai   +4 more
openaire   +3 more sources

Robustness evolution of collaborative innovation network in China’s smart grid industry

open access: yesSustainable Futures
Clarifying the evolution trend of network robustness is of great significance to how to protect and maintain the structure and performance of collaborative innovation networks of China's smart grid industry.
Yuan Tao
doaj   +1 more source

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