Results 21 to 30 of about 455,086 (317)

Development and Validation of Universal 3D Blast Fragmentation Model

Applied Sciences, 2023
The dominant technology in hard rock mining is drilling and blasting; therefore, the importance of fragment size estimation is an essential problem in the mining industry.
Veljko Lapčević, Slavko Torbica, Miloš Stojanović, Ivica Vojinović   +3 more
doaj   +1 more source

Impact of impactor shape and dimensions on dynamic rock fracture performance

Горное оборудование и электромеханика
The selection of effective methods and tools for the destruction of rocks, especially those of medium and high strength, is one of the main objectives of scientific research both in Russia and abroad.
Linnik Yu.N., Linnik V.Yu.
doaj   +1 more source

Experimental study of the influence of structural planes on the mechanical properties of sandstone specimens under cyclic dynamic disturbance

Energy Science & Engineering, 2020
Discontinuity‐controlled slopes constitute potentially fatal risks during exploitation activities in open‐pit mines and severely threaten the safe mining of collieries. To investigate the dynamic mechanical properties of rock with structural planes under
Han Du, Danqing Song, Zhuo Chen, Zizheng Guo   +3 more
doaj   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Study on the Relationship Between Porosity and Mechanical Properties Based on Rock Pore Structure Reconstruction Model

Applied Sciences
The influence of porosity on rock mechanical properties constitutes a critical research focus. This investigation explores the relationship between pore structure parameters and mechanical characteristics through reconstructed numerical models. The study
Nan Xiao, Jun-Qing Chen, Xiang Qiu, Fu Huang, Tong-Hua Ling   +4 more
doaj   +1 more source

Rock around Spain: historia, industria, escenas y medios de comunicación

InMediaciones de la Comunicación, 2017
El libro Rock around Spain (2013), editado por la Universitat de Lleida, apuesta a una aproximación transdisciplinar rica en matices conceptuales y escriturales, y cuenta con cuatro secciones “Historia, Industria, Escenas y Medios de comunicación”.
Álvaro Buela
doaj   +1 more source

Investigation of Nonlinear Flow in Discrete Fracture Networks Using an Improved Hydro-Mechanical Coupling Model

Applied Sciences, 2022
Fractures commonly exist in rock masses; the coalescence of fractures provides fluid flow pathways in a fractured rock mass and greatly increases the flow capacity of fractured rock.
Qun Sui, Weizhong Chen, Luyu Wang
doaj   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Effect of increasing mining rate on longwall coal mining – Western donbass case study

Studia Geotechnica et Mechanica, 2016
This paper presents the problems associated with the rapid change of the rock stress-strain state in terms of increasing the rate of coal mining.
Sdvyzhkova Olena, Patyńska Renata
doaj   +1 more source

A Unified Nonlinear Elastic Model for Rock Material

Applied Sciences, 2022
Under conditions of low or medium stress, rocks that are in the compression state exhibit perceivable nonlinear elastic characteristics. After a comprehensive review of the existing nonlinear elastic models of rocks and joints, we proposed a new unified ...
Chong Chen, Shenghong Chen, Yihu Zhang, Hang Lin, Yixian Wang   +4 more
doaj   +1 more source