Results 41 to 50 of about 2,479,486 (360)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Resonancias, 2021 At the end of 2017, discomforts among women musicians were publicly manifested due to the low presence of women in certain emblematic musical events. In a short time, this complaint became a shared claim, a focused questioning through which a series of ...
Mercedes Liska
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Revista Facultad de Ingeniería, 2019 Pillar replacement in mining works is a technique of using the pillars that are part of the support structures having a high degree of mineralization, which attracts economic interest.
Claudia Yasmin Montaño-Chinchilla +3 more
doaj +1 more source
Albuquerque, 2020 Resenha do livro Rock cá, rock lá: a produção roqueira no Brasil e em Portugal na imprensa – 1970/1985.
Edvaldo Correa Sotana
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Applied Sciences, 2023 To investigate the effects of long-term freeze–thaw cycles on the physical and mechanical properties as well as the attenuation trend of rocks, this study conducted saturated freeze–thaw tests on coarse sandstone and fine sandstone samples collected from
Liping Wang +4 more
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Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Time-based Signal Processing and 'Shape' in Alternative Rock Recordings
IASPM Journal, 2016 This article considers the impact of time-based signal processors on the ‘shape’ of alternative rock recordings. The concept of musical ‘shape’ is considered here as both textural and gestural.
Samantha Bennett
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