Results 41 to 50 of about 686,858 (318)

Prevalence of amenorrhea in elite female competitive climbers

open access: yesFrontiers in Sports and Active Living, 2022
Elite competitive sport climbers exhibit a high strength-to-weight ratio and are reported in the literature to be lighter and leaner than their athletic counterparts.
Lanae Joubert   +11 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

A cluster analysis of harmony in the McGill Billboard dataset

open access: yesEmpirical Musicology Review, 2020
We set out to perform a cluster analysis of harmonic structures (specifically, chord-to-chord transitions) in the McGill Billboard dataset, to determine whether there is evidence of multiple harmonic grammars and practices in the corpus, and if so, what ...
Kris Shaffer   +8 more
doaj   +1 more source

Rock's pill that rocked the world

open access: yesSouth African Medical Journal, 2010
I was a rookie doctor on the goldmines in the early 1960s. Part of my duties was to look after the families in the villages of the Anglo American mines at Welkom in the Free State. Their invariably large numbers of children prompted me to enquire whether they wished to have assistance in family planning.
openaire   +3 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Effect of Empty-Hole on Blasting-Induced Damage Evolution and Dynamic Response of Rock

open access: yesGaoya wuli xuebao
Aiming at the issue that traditional perimeter blasting easily induces random crack damage in surrounding rocks, this study conducts an in-depth analysis of the damage evolution laws and dynamic response characteristics in empty-hole directional blasting
Tao LI, Yu NI, Zhiliang WANG
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

PRÓBA CHARAKTERYSTYKI ROCKOWYCH STACJI RADIOWYCH W POLSCE

open access: yesCivitas et Lex, 2018
The offer of Polish radio stations is relatively extensive. Polish radio market offers many radio stations with diversified music profiles. This collection also includes rock radio stations.
Łukasz Grochulski
doaj   +1 more source

Corpos (não tão) dóceis

open access: yesAlbuquerque, 2020
Os corpos da juventude contracultural e roqueira tornaram-se protagonistas nos anos pós-segunda guerra mundial. Galgaram tal posição a despeito da coerção e censura ditadas pelos mecanismos de disciplinarização e processos civilizadores da moderna ...
Manoel Ruiz Corrêa Martins
doaj   +1 more source

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