Results 31 to 40 of about 686,858 (318)
Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Rock e insurgências nos anos 1960
Antropolítica : Revista Contemporânea de Antropologia, 2021 O artigo aborda a explosão do rock no contexto mais amplo das convulsões políticas e das mudanças culturais dos anos 1960. A enorme popularidade do rock incluiu, no mundo inteiro, vastos contingentes com aspirações diversificadas e arrebatou corações e ...
Luis Carlos Fridman
doaj +1 more source
Effect of contact characteristics on the self-rotation performance of conical picks based on impact dynamics modelling [PDF]
Royal Society Open Science, 2020 Conical picks have a harsh working environment and 70% of their failures are caused by wear. It has been found that conical picks can rotate while interacting with the working material.
Xiaohui Liu, Qi Geng
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Reinforcement design and control of rock slopes above tunnel portals in Northern Italy [PDF]
, 2004 The stability features of slopes located above the portals of tunnels along important roads are here presented, together with two examples for reinforcement and protection works.
Del Greco, O. +2 more
core +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Fractal and FractionalTo study the effects of rock models with different fractal dimensions on their mechanical properties and fracture behavior, three representative numerical rock models, including the digital texture model, the Voronoi polygon model, and the Weibull ...
Run Shi, Huaiguang Xiao
doaj +1 more source
The influence of microwave radiation on the failure of rocks [PDF]
Acta Montanistica Slovaca, 2000 The heating and processing of materials using microwaves becomes increasingly popular for industrial applications. Compared to conventional heating, microwave processing can provide a rapid, the production of materials with unique properties, and ...
Lovás Michal +2 more
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