Results 51 to 60 of about 686,858 (318)
FEBS Open Bio, EarlyView.We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa +2 more
wiley +1 more source
Rock the Rock of Atherosclerosis [PDF]
Journal of Vascular Medicine & Surgery, 2013 The Rho-Associated Coiled-Coil Containing Protein Kinase (ROCK1 and ROCK2) were one of the downstream effectors of the small GTPase Rho. The Rho/ROCK pathway plays an important role in mediating multiple cellular processes, including endothelial dysfunction, the proliferation and migration of smooth muscle cells, foam cell formation, and arterial ...
openaire +1 more source
Development of human monoclonal antibodies against TARM1 by yeast display
FEBS Open Bio, EarlyView.Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
Deep hole drilling modern disintegration technologies in process of HDR technology [PDF]
Acta Montanistica Slovaca, 2012 Through physical and chemical effect on rock, the new technologies are achieving good drilling results at higher progressivespeeds and at shorter time than the conventional rotation drilling.
Gabriel Wittenberger +2 more
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FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Contemporary Art and Rock, some relations
Visualidades, 2011 This article investigates some relations between contemporary art and rock, from a collection of examples of the involvement between artists and rockers through history. Notably Pop Art, punk, Conceptual Art and the figure of Hélio Oiticica.
Leonardo Felipe
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Yankuang ceshi, 2020 BACKGROUND The sampling weight can be as low as milligram level when the contents of rare earth elements in rock and soil samples are determined by inductively coupled plasma-mass spectrometry (ICP-MS).
WANG Na +5 more
doaj +1 more source
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
Bit Selection of Tight Gravel-bearing Sandstone Formation in Dongsheng Gas Field
Shiyou jixie, 2016 Due to high density,hardness and abrasiveness of rocks in Dongsheng Gas Field,the bit is worn out and the rate of penetration is low.In order to solve this problem,a rock drillability value calculation model is built based on the relation between ...
Chen Xiaohua +3 more
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