Results 31 to 40 of about 455,086 (317)

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Crisis contracultural y rock en la Ciudad de México: relaciones de producción, reproducción viva y sociabilidad. 1972-1977

open access: yesHistoria y Sociedad, 2020
Este artículo reconstruye un periodo poco explorado de la historia musical en México. El texto analiza la transformación de las relaciones de producción de la industria musical en la capital en el curso de descomposición de la contracultura, de ...
José Rodrigo Moreno-Elizondo
doaj   +1 more source

Rock Emissivity Measurement for Infrared Thermography Engineering Geological Applications

open access: yesApplied Sciences, 2021
Infrared thermography is a growing technology in the engineering geological field both for the remote survey of rock masses and as a laboratory tool for the non-destructive characterization of intact rock.
Simone Mineo, Giovanna Pappalardo
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

La exclusión de artistas mujeres en los festivales: políticas de género y relevamientos cuantitativos en el ámbito musical profesional de la Argentina (2017-2019)

open access: yesResonancias, 2021
At the end of 2017, discomforts among women musicians were publicly manifested due to the low presence of women in certain emblematic musical events. In a short time, this complaint became a shared claim, a focused questioning through which a series of ...
Mercedes Liska
doaj   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Design of an economically feasible support for the replacement of pillars in Providencia Mine, Antioquia - Stage 1

open access: yesRevista Facultad de Ingeniería, 2019
Pillar replacement in mining works is a technique of using the pillars that are part of the support structures having a high degree of mineralization, which attracts economic interest.
Claudia Yasmin Montaño-Chinchilla   +3 more
doaj   +1 more source

Rock, mídia e política

open access: yesAlbuquerque, 2020
Resenha do livro Rock cá, rock lá: a produção roqueira no Brasil e em Portugal na imprensa – 1970/1985.
Edvaldo Correa Sotana
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

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