Results 41 to 50 of about 1,002,663 (347)
Molecular Oncology, EarlyView.TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair +17 more
wiley +1 more source
Rock critics as 'Mouldy Modernists'
PORTAL: Journal of Multidisciplinary International Studies, 2011 Contemporary rock criticism appears to be firmly tied to the past. The specialist music press valorise rock music of the 1960s and 1970s, and new emerging artists are championed for their ‘retro’ sounding music by journalists who compare the sound of ...
Becky Shepherd
doaj
Rock and Roll Styles and Genres in Poland (1957–1973)
Musicology Today, 2016 This paper describes the process of establishing rock and roll styles and genres (as defined by Allan F. Moore) in Polish musical culture. My Ph.D. research has revealed three phases in this process. Phase 1: imitation (1957-1962), phase 2: Polonisation (
Gradowski Mariusz
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Time-based Signal Processing and 'Shape' in Alternative Rock Recordings
IASPM Journal, 2016 This article considers the impact of time-based signal processors on the ‘shape’ of alternative rock recordings. The concept of musical ‘shape’ is considered here as both textural and gestural.
Samantha Bennett
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Molecular Oncology, EarlyView.Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu +11 more
wiley +1 more source
Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
wiley +1 more source
La tragedia de Cromañón: un caso de religiosidad popular urbana [PDF]
Aposta, 2007 El día 30 de Diciembre de 2004 se desataba un incendio provocado por una bengala en un recital que el grupo de rock Callejeros llevaba a cabo en el local La República de Cromañón, ubicado en el barrio porteño de Once frente a la plaza Miserere; en este ...
Maximiliano E. Korstanje
doaj
Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren +16 more
wiley +1 more source
Frontiers in Earth Science, 2023 To fulfill the requirement for deformation measurement within the failure area during rock failure, a newly developed digital image algorithm, known as the corner correlation method, was implemented.
Xingui Zhou +6 more
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JAK-STAT, 2013 The endocrine cytokine leptin is mainly secreted by white adipose tissue and plasma leptin levels positively correlate with body fat mass. Via its action on neurons in the hypothalamic arcuate nucleus (ARC), leptin regulates body weight by stimulating energy expenditure and inhibiting food intake.
Jan Tavernier, Frank Peelman
openaire +3 more sources