Results 41 to 50 of about 2,889,522 (389)

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

open access: yesFEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää   +2 more
wiley   +1 more source

Rock's pill that rocked the world

open access: yesSouth African Medical Journal, 2010
I was a rookie doctor on the goldmines in the early 1960s. Part of my duties was to look after the families in the villages of the Anglo American mines at Welkom in the Free State. Their invariably large numbers of children prompted me to enquire whether they wished to have assistance in family planning.
openaire   +4 more sources

A New Flattened Cylinder Specimen for Direct Tensile Test of Rock

open access: yesSensors, 2021
In recent decades, researchers have paid more attention to the indirect tensile test than to the direct tensile test (DTT) of rocks, mainly due to difficulties in the alignment and the stress concentration at the end of an intact cylindrical specimen. In
Qiuhua Rao   +4 more
doaj   +1 more source

Vortices determine the dynamics of biodiversity in cyclical interactions with protection spillovers [PDF]

open access: yes, 2015
If rock beats scissors and scissors beat paper, one might assume that rock beats paper too. But this is not the case for intransitive relationships that make up the famous rock-paper-scissors game.
Perc, Matjaz, Szolnoki, Attila
core   +2 more sources

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

You say you want a revolution?: popular music and revolt in France, The United States, and Britain during the late 1960s

open access: yesHistoria Actual On-Line, 2009
Es casi imposible entender los movimientos juveniles de protesta de los años 60 sin un cierto aprecio de la importancia de la música popular de esa década.
Stuart P. Mitchell
doaj  

Archaeal protein containing domain of unknown function 2193 undergoes oligomeric reconfiguration upon iron–sulfur cluster binding

open access: yesFEBS Letters, EarlyView.
This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter   +8 more
wiley   +1 more source

A TREATISE ON ROCKS, ROCK-WEATHERING AND SOILS. [PDF]

open access: yesJournal of the American Chemical Society, 1905
n ...
openaire   +2 more sources

Underground mining of ore deposits while keeping the earth's surface

open access: yesГорные науки и технологии, 2018
In market economy, quality indicators of the extracted minerals are of particular importance. Decreasing ore losses and dilution can be achieved by controlling stress and strain using the residual bearing capacity of the broken rocks with the priority ...
V. I. Golik   +3 more
doaj   +1 more source

Application of Cycle-Flow Technology in Coal Mines

open access: yesProceedings of the International Conference on Applied Innovations in IT, 2023
This article discusses, describes and analyzes the main problems of open mining in overburden work with the transportation of rock mass at the Angren coal open pit.
Javokhir Toshov   +3 more
doaj   +1 more source

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