Results 51 to 60 of about 1,002,663 (347)
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche+8 more
wiley +1 more source
Relevance of work is caused by need of a solution of the problem of increase of efficiency of drilling of deep wells for solid anisotropic rocks. Work purpose: Research and development of new model of a diamond drill bit for drilling of solid anisotropic
Vyacheslav Neskoromnykh+4 more
doaj
Effect of Water Saturation on Stress-Strain Curve of Rocks in Uniaxial Compression
The effect of water on the mechanical properties of rocks, such as strength and Young's modulus, has been investigated in many studies. To understand the mechanism of the effect of water on the mechanical behavior of rocks, not only these mechanical
Minami KATAOKA+3 more
doaj +1 more source
Heterogeneous rock contains numerous pre-existing three-dimensional (3D) cracks, which control its mechanical and fracturing properties. Considerable effort has been devoted to studying the volumetric fracturing behaviour of rock under static loading ...
Tao Zhou, Jianbo Zhu, Heping Xie
semanticscholar +1 more source
In R-parity conserving supersymmetric (SUSY) models the lightest SUSY particle (LSP) is stable and a candidate for dark matter. Depending on the coupling and mass of this particle the life time of the next-to-lightest SUSY particle (NLSP) may be large compared to experimental time scales.
openaire +5 more sources
Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza+3 more
wiley +1 more source
Methods and Points of Attention for the Direct Tension Test on Rock
Compared to uniaxial or triaxial compression tests on rocks, direct tension tests on rocks are not common in practice. As is well known, the reasons are because underground rock masses are usually under compressive stress state and/or because the direct ...
Kimihiro HASHIBA+5 more
doaj +1 more source
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh+5 more
wiley +1 more source
Process of quantitative evaluation of validity of rock cutting model [PDF]
Most of complex technical systems, including the rock cutting process, are very difficult to describe mathematically due to limitedhuman recognition abilities depending on achieved state in natural sciences and technology.
Jozef Futó+3 more
doaj
Dependence of Uniaxial Compressive Strength of Sanjome Andesite on Loading Rate and Water Saturation
It is known that the rock strength increases with an increase in loading rate. Many studies on the loadingrate dependence of rock strength have been performed under two environments, namely water-saturated and airdried conditions, and the loading-rate ...
Minami KATAOKA+2 more
doaj +1 more source