Results 51 to 60 of about 1,002,663 (347)

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

open access: yesMolecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche   +8 more
wiley   +1 more source

Development and pilot studies of the features of a diamond drill crown operation when drilling in solid anisotropic rocks

open access: yesИзвестия Томского политехнического университета: Инжиниринг георесурсов, 2019
Relevance of work is caused by need of a solution of the problem of increase of efficiency of drilling of deep wells for solid anisotropic rocks. Work purpose: Research and development of new model of a diamond drill bit for drilling of solid anisotropic
Vyacheslav Neskoromnykh   +4 more
doaj  

Effect of Water Saturation on Stress-Strain Curve of Rocks in Uniaxial Compression

open access: yesJournal of MMIJ, 2017
The effect of water on the mechanical properties of rocks, such as strength and Young's modulus, has been investigated in many studies. To understand the mechanism of the effect of water on the mechanical behavior of rocks, not only these mechanical
Minami KATAOKA   +3 more
doaj   +1 more source

Mechanical and Volumetric Fracturing Behaviour of Three-Dimensional Printing Rock-like Samples Under Dynamic Loading

open access: yesRock Mechanics and Rock Engineering, 2020
Heterogeneous rock contains numerous pre-existing three-dimensional (3D) cracks, which control its mechanical and fracturing properties. Considerable effort has been devoted to studying the volumetric fracturing behaviour of rock under static loading ...
Tao Zhou, Jianbo Zhu, Heping Xie
semanticscholar   +1 more source

Supersymmetry on the Rocks

open access: yesJournal of Physics: Conference Series, 2007
In R-parity conserving supersymmetric (SUSY) models the lightest SUSY particle (LSP) is stable and a candidate for dark matter. Depending on the coupling and mass of this particle the life time of the next-to-lightest SUSY particle (NLSP) may be large compared to experimental time scales.
openaire   +5 more sources

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

open access: yesMolecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza   +3 more
wiley   +1 more source

Methods and Points of Attention for the Direct Tension Test on Rock

open access: yesJournal of MMIJ, 2016
Compared to uniaxial or triaxial compression tests on rocks, direct tension tests on rocks are not common in practice. As is well known, the reasons are because underground rock masses are usually under compressive stress state and/or because the direct ...
Kimihiro HASHIBA   +5 more
doaj   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

open access: yesMolecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh   +5 more
wiley   +1 more source

Process of quantitative evaluation of validity of rock cutting model [PDF]

open access: yesActa Montanistica Slovaca, 2012
Most of complex technical systems, including the rock cutting process, are very difficult to describe mathematically due to limitedhuman recognition abilities depending on achieved state in natural sciences and technology.
Jozef Futó   +3 more
doaj  

Dependence of Uniaxial Compressive Strength of Sanjome Andesite on Loading Rate and Water Saturation

open access: yesJournal of MMIJ, 2018
It is known that the rock strength increases with an increase in loading rate. Many studies on the loadingrate dependence of rock strength have been performed under two environments, namely water-saturated and airdried conditions, and the loading-rate ...
Minami KATAOKA   +2 more
doaj   +1 more source

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