Results 61 to 70 of about 1,002,663 (347)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Measurement of Suction Pressure Generated in the Process of Frost Heaving in Rock

open access: yesJournal of MMIJ, 2017
Recently it has been found that frost heave phenomena can be seen not also in soil but also in rock. It is obvious, however, that the number of researches on frost heaving in rock is much less than that of researches on frost heaving in soil.
Dai NAKAMURA   +5 more
doaj   +1 more source

Metamorphism of rocks and rock flowage

open access: yesGeological Society of America Bulletin, 1897
At head of title: Bulletin of the Geological Society of America, vol. 9, May 19, 1898. ; Caption-title. ; Mode of access: Internet.
openaire   +3 more sources

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

open access: yesFEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran   +3 more
wiley   +1 more source

Rocking the curve

open access: yesTrends in Microbiology, 2004
Quantifying microbial growth is of primary interest in microbiology and is routinely involved in a diversity of studies, such as comparing and/or contrasting strains and/or species, competition associated with co-infections, assessments of risks related to food contamination, testing drug efficacy, or the development of candidate vaccines [1–4].
/Choisy, Marc   +3 more
openaire   +4 more sources

Biophysical characterization and ion transport with cell‐based and proteoliposome reconstitution assays of invertebrate K+‐Cl− cotransporters

open access: yesFEBS Open Bio, EarlyView.
The K+‐Cl− cotransporters (KCCs) facilitate the symport of ions across the plasma membrane. They participate in physiological processes including neuronal regulation. Here, we characterized KCCs from Drosophila and Hydra vulgaris. Comparative analyses of transporters provide insights into the mechanism of KCC ion transport, regulation, and evolution ...
Satoshi Fudo   +4 more
wiley   +1 more source

Rocking pneumonia

open access: yesPneumonia, 2017
Ever since Chuck Berry coined the term "rocking pneumonia" in his 1956 song "Roll over Beethoven", pneumonia has been mentioned frequently in modern blues and rock songs. We analyzed the lyrics of these songs to examine how various elements of pneumonia have been represented in popular music, specifically the cause of pneumonia, the risk groups ...
Ger T. Rijkers, Maria Rodriguez Gomez
openaire   +3 more sources

Matrix: a complex amalgam of structures and functions in tumor microenvironment

open access: yesFEBS Open Bio, EarlyView.
The matrix is a dynamic, intricate three‐dimensional mesh of biomolecules with both structural and functional properties. This review deals with the complexity of this ‘molecular amalgam’ in the tumor microenvironment and highlights its importance in the maintenance and evolution of tumors by describing certain matrix biomolecules, such as ...
Spyros S. Skandalis   +3 more
wiley   +1 more source

Characterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activity

open access: yesFEBS Open Bio, EarlyView.
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo   +11 more
wiley   +1 more source

Uranium thorium and potassium contents analysis of rocks in Changwat Narathiwat by gamma spectrometry [PDF]

open access: yesSongklanakarin Journal of Science and Technology (SJST), 2002
Quantitative analysis of three radioactive elements (potassium, equivalent uranium, and equivalent thorium) in the granite rocks of the Triassic Age at 24 locations in Narathiwat province was carried out by using a gamma counter.
Kaewtubtim, P., Changkain, S.
doaj  

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