Results 31 to 40 of about 3,819,291 (249)

Numerical Simulations and Experiments on Single-Tooth Rock-Breaking

Machines, 2022
The rock-breaking efficiency of a drilling tool directly affects the production costs and progress of foundation construction. It is essential to understand the mechanism of mechanical rock-breaking to improve rock-breaking efficiency.
Heyuqiu Li, Jie Wang, Qi Mei, Kunlan Huang, Qingyi Luo, Jie Dong   +5 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Leveraging Symbolic Artificial Intelligence and Fuzzy Logic for Materials Science: A Review of Methods, Challenges, and Applications to Scarce and Imperfect Experimental Data

Advanced Engineering Materials, EarlyView.
This article explores the transformative potential of symbolic artificial intelligence (AI) in the field of materials science, particularly in leveraging experimental data. The article presents several symbolic AI models and discusses their applications in materials science.
Ahmed Amrani, Mohamed‐Ali Belloum, Laurence Boudet, Valentin Fouillard, Edwin Friedmann, Guillaume Lacharme, Ali Mahmoud, Jean‐Philippe Poli   +7 more
wiley   +1 more source

Rock-breaking mechanism and experimental analysis of confined blasting of borehole surrounding rock

, 2017
The rock-breaking mechanism and effect of confined blasting were analysed by blasting and impact dynamic mechanics, fluid dynamic mechanics, fracture mechanics as well as blasting experiment.
Liu Changyou, Yang Jingxuan, Yu Bin
core   +1 more source

Dynamic Rock-Breaking Process of TBM Disc Cutters and Response Mechanism of Rock Mass Based on Discrete Element

, 2022
Rock-breaking efficiency of full-face rock tunnel boring machine (TBM) is closely related to the performance of the disc cutter and the characteristics of the rock mass.
Canxun Du, Sanlin Du, Yanwen Zhu, Qinglong Zhang, Zhihao Jin, Kun Shao   +5 more
core   +1 more source

Numerical Simulation Study on Characteristics of Tight Hard Sand Broken by Axe-shaped PDC Cutter

Shiyou jixie, 2021
The study on the specific rock breaking mechanism of axe-shaped PDC cutter in the existing literatures is relatively less, the rock breaking characteristic test data are mostly for field application data, and there is short of theoretical basis of tooth ...
Zhao Runqi, Chen Zhenliang, Shi Huaizhong, He Wenhao, Shi Xingxing, Chen Han   +5 more
doaj  

Ultrasonic-Assisted Rock-Breaking Technology and Oil and Gas Drilling Applications: A Review

Energies, 2022
High-efficiency rock-breaking is a problem that has long been studied in the oil- and gas-drilling industry. The successful use of ultrasonic technology in related fields has prompted us to study how to introduce ultrasonic technology into rock-breaking ...
Jinyu Feng, Tie Yan, Yang Cao, Shihui Sun   +3 more
doaj   +1 more source

A Multi‐Scale Machine Learning Framework for the Inverse Design of High Entropy Alloys

Advanced Engineering Materials, EarlyView.
High‐entropy alloys offer vast potential for various applications, including electrocatalysis; however, their compositional complexity challenges conventional screening. We introduce an inverse‐design framework combining two neural networks to determine optimal compositions and reconstruct nanoparticle geometry from targeted properties and conventional
Mikael Takoutsin, Marta Campolucci, Nicolas de Andrade Ishiki, Nathan Mirgot, Nadir Zhamantay, Frédéric Kanoufi, Jennifer Peron, Jean Charlety, Emiliano Fonda, Valérie Briois, Marco Faustini, Maria‐Letizia De Marco, Christine Goyhenex, Ovidiu Ersen, Hervé Bulou   +14 more
wiley   +1 more source

Numerical Investigation of Rock Breaking Mechanisms by High Pressure Water Jet [PDF]

, 2015
Many factors and complexities are involved in breaking rock with a high-pressure water jet, which has made it difficult to explain the rock breaking internal mechanisms.
Chen, Hailong, Gao, Zhihan, Li, Zhaomin, Sun, Yuanyuan   +3 more
core   +1 more source

The Modelling of Rock Fragmentation Mechanisms by Carbide Buttons Using the 3D Discrete Element Method

Applied Sciences, 2023
Button cutters are commonly used in hard rock drilling because the inserted carbide buttons provide exceptional wear resistance, impact resistance, and high strength in challenging geological formations.
Yanan Ma, Qiuming Gong, Xiaoxiong Zhou, Lijun Yin, Hongsu Ma   +4 more
doaj   +1 more source