Results 31 to 40 of about 1,132,394 (292)
Advances in Materials Science and Engineering, 2018 To investigate the specific energy consumption (SE) of rock breakage by cutting heads assisted by different types of waterjet and to identify optimal waterjet parameters and assistance types, rock cutting with and without waterjets was carried on a rock ...
Hongxiang Jiang, Deguang Meng
doaj +1 more source
Study on the Improved Method of Wedge Cutting Blasting with Center Holes Detonated Subsequently
Energies, 2022 To acquire a satisfying cutting effect during medium-length hole blasting driving of rock tunnels, an improved wedge cutting blasting method with supplementary blasting of the center holes was proposed.
Bing Cheng +5 more
doaj +1 more source
Investigation of the Cross-Cutting Polycrystalline Diamond Compact Bit Drilling Efficiency
Shock and Vibration, 2021 The parallel track scraping principle of conventional PDC bits largely limits the cutting efficiency and working life in deep formations. Cross-cutting polycrystalline diamond compact (PDC) bit may be an efficient drilling tool that increases the rock ...
Chun-Liang Zhang +5 more
doaj +1 more source
An Innovative Experimental Study of Corner Radius Effect on Cutting Forces [PDF]
, 2014 The cutting forces are often modelled using edge discretisation methodology. In finish turning, due to the smaller corner radii, the use of a local cutting force model identified from orthogonal cutting tests poses a significant challenge. In this paper,
BISSEY BRETON, Stéphanie +4 more
core +1 more source
Energy Science & Engineering, 2022 Combining well‐drilling hammers with polycrystalline diamond compact bits to break rock under cutting load and impact load is an effective way to improve drilling efficiency.
Heng Zhang +6 more
doaj +1 more source
Considerations for Discrete Element Modeling of Rock Cutting [PDF]
, 2013 This study attempts to build a framework within the Discrete Element Method (DEM) to produce a reliable predictive tool in rock cutting applications, such that the cutting forces and fragmentation process are reasonably estimated. The study is limited to
Mendoza Rizo, Jorge Alejandro
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Slant Angle and Its Influence on Rock Cutting Performance
Advances in Civil Engineering, 2018 Rock cutting is an important aspect of the civil engineering, for example, tunnelling. To improve cutting efficiency, it is important to understand the rock failure (fracture) mechanisms and the influences of cutting parameters on rock fracture behaviour.
Yong Sun, Xingsheng Li
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source