Results 61 to 70 of about 382,665 (308)

Research status and prospect of rock breaking form in mechanized excavation of mining hard rock roadway

open access: yesMeitan kexue jishu
Rapid excavation of hard rock tunnels was a crucial aspect in achieving intelligent and efficient coal mining. Cantilever roadheaders, TBMs, and bottom cutting equipment are all attempting to address this challenge.
Chao LI   +4 more
doaj   +1 more source

GPGPU-parallelised hybrid finite-discrete element modelling of rock chipping and fragmentation process in mechanical cutting

open access: yesJournal of Rock Mechanics and Geotechnical Engineering, 2020
Mechanical cutting provides one of the most flexible and environmentally friendly excavation methods. It has attracted numerous efforts to model the rock chipping and fragmentation process, especially using the explicit finite element method (FEM) and ...
Mojtaba Mohammadnejad   +4 more
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Predicting Loss of Ambulation in Limb Girdle Muscular Dystrophy R9

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Limb girdle muscular dystrophy type R9 (LGMDR9) results from biallelic variants in FKRP. There is limited data to predict loss of ambulation (LOA) among those with LGMDR9. Methods Participants in an ongoing dystroglycanopathy natural history study (NCT00313677) with FKRP variants who had achieved ambulation and were more than 3 ...
Chandra L. Miller   +6 more
wiley   +1 more source

Suitability of natural rocks as materials for cutting tools

open access: yesSN Applied Sciences, 2021
This study presents an investigation of the usability and suitability of natural rocks as cutting tool materials. Therefore, indexable inserts are manufactured from eight different rocks and two mono minerals in this study and are used for turning of an ...
Berend Denkena   +5 more
doaj   +1 more source

Overview of technologies for constructing the facilities at the Dniester pumped storage power station [PDF]

open access: yes, 2019
Purpose. Perform an overview of the construction technologies and substantiate the effectiveness of the Ukrainian experience in building a pumped storage power station (PSPS) on the Dniester River in difficult engineering-geological conditions with the ...
Horbatiuk, Yu   +4 more
core   +1 more source

Prognostic Value of Neurofilament Light Chain and Glial Fibrillary Acidic Protein in ALD‐Related Myelopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak   +4 more
wiley   +1 more source

An experimental study of the carbonation of serpentinite and partially serpentinised peridotites [PDF]

open access: yes, 2017
In situ sequestration of CO2 in mantle peridotites has been proposed as a method to alleviate the amount of anthropogenic CO2 in the atmosphere. This study presents the results of 8-month long laboratory fluid-rock experiments on representative mantle ...
Bevan   +34 more
core   +3 more sources

Multimodal Data‐Driven Microstructure Characterization

open access: yesAdvanced Engineering Materials, EarlyView.
A self‐consistent autonomous workflow for EBSP‐based microstructure segmentation by integrating PCA, GMM clustering, and cNMF with information‐theoretic parameter selection, requiring no user input. An optimal ROI size related to characteristic grain size is identified.
Qi Zhang   +4 more
wiley   +1 more source

Влияние технико-технологических особенностей режущей структуры породоразрушающего инструмента типа PDC на разрушение горной породы в процессе бурения скважин [PDF]

open access: yes, 2017
Доля бурения скважин долотами PDC неуклонно растет, в настоящий момент процент использования породоразрушающего инструмента типа PDC для бурения скважин любого типа сложности составляет 95%.
Анисимов, Александр Владимирович
core  

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