Results 91 to 100 of about 2,680,418 (361)

Investigating the Effects of Cement and Polymer Grouting on the Shear Behavior of Rock Joints [PDF]

, 2022
Milad Abolfazli, Milad Bazli, Hossein Heydari, Ahmad Fahimifar   +3 more
openalex   +1 more source

Pan‐3D Genome Analysis Reveals the Roles of Structural Variation in Chicken Chromatin Architectures, Domestication and Production Traits

Advanced Science, EarlyView.
This study firstly presents a comprehensive and high‐resolution pan‐3D genome resource in chicken. Our findings reveal the role of structural variations in 3D genome architectures, and how they influence the domestication process and production traits at the 3D genome level.
Zhen Zhou, Danfeng Cai, Changbin Zhao, Siyu Zhang, Jiahao Li, Zhaofeng Zhang, Shaofen Kong, Xin Yang, Xiaoli Zhou, Farhad Bordbar, Fayi Chen, Yaohuan Xu, Zhe Zhang, Lihong Gu, Zhenhui Li, Xiquan Zhang, Wen Luo, Jingting Shu, Bolin Cai, Qinghua Nie   +19 more
wiley   +1 more source

Experimental Investigation on the Effects of Cutting Direction and Joint Spacing on the Cuttability Behaviour of a Conical Pick in Jointed Rock Mass

Applied Sciences
In this study, a series of rock cutting tests was conducted using a conical pick to investigate the effect of joints on roadheader performance. Tests were performed on intact rock and jointed rock mass specimens with three different joint spacings.
Han-Eol Kim, Min-Seong Kim, Wan-Kyu Yoo, Chang-Yong Kim   +3 more
doaj   +1 more source

Investigation of Rock Joint and Fracture Influence on Delayed Blasting Performance

, 2023
Pengfei Zhang, Runcai Bai, Xue Sun, Tianheng Wang   +3 more
openalex   +2 more sources

Integrating Spatial Proteogenomics in Cancer Research

Advanced Science, EarlyView.
Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang, Yang Wu, Feng Zhang, Parthiban Periasamy, Haiyue You, Denise Goh, Rachel Elizabeth Ann Fincham, Xin Ning, Danping Wu, Lu Liu, Ying Jiang, Zhiwen Qian, Joe Yeong, Yan Zhang   +13 more
wiley   +1 more source

Dynamic Response Law of Nonpersistent Jointed Rock Mass Under Normal Impact Load

Shock and Vibration
Normal dynamic mechanical characteristics of the jointed rock mass are of great significance for studying the working state of rock mass with nonpersistent joint.
Xianshi Deng, Yan Chang, Rong Hu, Heng Deng, Duofang Lu   +4 more
doaj   +1 more source

Inhibiting cGAS‐STING to Preserve Mitochondrial–Nuclear Communication and Stemness in Young Tendon Stem Cells: A Hydrogel Strategy against Age‐Related Tendinopathy

Advanced Science, EarlyView.
A dual‐targeting strategy to rejuvenate aged tendons. A reactive oxygen species (ROS)‐responsive hydrogel co‐delivers a selenium nanozyme (scavenges ROS) and a STING inhibitor to tendon stem cells. This combined action restores mitochondria–nucleus communication, alleviates cellular senescence, and rejuvenates tendon regeneration, offering a novel ...
Zhuo Zhang, Weiyong Song, Heng Yin, Yi Wang, Yi Zou, Yuling Li, Yue Luo, Chao Xiang, Xiaoqin Liu, Yan Xiong, Yong Wang, Ke Jiang   +11 more
wiley   +1 more source

Numerical investigation of bolted rock joints under varying normal stress and joint roughness coefficient conditions

Frontiers in Earth Science
Rock masses are formed through long-term, complex geological processes, and the presence of joints significantly reduces their strength and increases their deformation.
Zhiyong Wang, Zhiyong Wang, Liyun Liao, Liyun Liao, Shiyi Guo, Shiyi Guo, Hanfang Zheng, Xuezhen Wu, Xuezhen Wu   +8 more
doaj   +1 more source

A New Representative Sampling Method for Series Size Rock Joint Surfaces. [PDF]

Sci Rep, 2020
Huang M, Hong C, Ma C, Luo Z, Du S, Yang F.   +5 more
europepmc   +1 more source

Hepatocyte BDNF Acts as a Novel Immune Checkpoint to Restrain TLR4‐Mediated Acute Hepatitis

Advanced Science, EarlyView.
This study identifies hepatocyte‐derived BDNF as an endogenous TLR4 antagonist that alleviates acute hepatitis. BDNF is downregulated in hepatocytes via REST‐mediated transcriptional repression during ALI/ALF. Mechanistically, BDNF binds to TLR4 on macrophages to suppress inflammation.
Weiwei Zhu, Yaqian Cui, Yongqiang Zhou, Yihui Zheng, Lijiang Huang, Leiming Jin, Qianhui Zhang, Pan Chen, Mengsha Lin, Jiaxi Ye, Yongqiang Xiong, Joo Young Huh, Xiang Hu, Xiaokun Li, Wu Luo, Guang Liang   +15 more
wiley   +1 more source