Results 91 to 100 of about 464,941 (308)
Classification of filled joint based on the characteristics of its constitutive components [PDF]
, 2003 Filled joints in rock mass pose a number of constructional problems. When filled joints are reckoned to be critical to an engineering structure, their behaviours are often studied using expensive in-situ testing and complex full-scale physical modelling.
Kassim, Azman +3 more
core
Influence of time-dependence on failure of echelon rock joints through a novel DEM model [PDF]
, 2015 This is an Accepted Manuscript of an article published by Taylor & Francis Group in [European Journal of Environmental and Civil Engineering] on [September 2015], available online at: http://www.tandfonline.com/10.1080/19648189.2015.1064624This article ...
Jiang, Mingjing +4 more
core +4 more sources
Hepatocyte BDNF Acts as a Novel Immune Checkpoint to Restrain TLR4‐Mediated Acute Hepatitis
Advanced Science, EarlyView.This study identifies hepatocyte‐derived BDNF as an endogenous TLR4 antagonist that alleviates acute hepatitis. BDNF is downregulated in hepatocytes via REST‐mediated transcriptional repression during ALI/ALF. Mechanistically, BDNF binds to TLR4 on macrophages to suppress inflammation.
Weiwei Zhu +15 more
wiley +1 more source
Numerical simulations on shear behaviour of rock joint network under constant normal stiffness conditions. [PDF]
PLoS One, 2023 Han G +6 more
europepmc +1 more source
Advanced Science, EarlyView.Gastric cancer‐derived exosomal TAGLN2 is identified as a key mediator of vascular reprogramming, with significantly elevated levels detected in patient serum. Independent of canonical SEMA4D signaling, it nucleates a cytoplasmic TAGLN2/NRP1/SEMA4D ternary complex that dually activates YAP, promoting angiogenesis, vascular dysfunction, and metastasis ...
Shuqi Yu +7 more
wiley +1 more source
Application of discrete fracture networks (DFN) in the stability analysis of Delabole Slate Quarry, Cornwall, UK [PDF]
, 2016 This is the author accepted manuscript. The final version is available from ARMA.50th US Rock Mechanics/Geomechanics Symposium, Houston, USA, 26-29 June 2016The failure mechanism of rock slopes is mainly controlled by the strength and orientation of ...
Coggan, JS, Elmo, D, Havaej, M, Stead, D
core
Impact of mechanical heterogeneity on joint density in a welded ignimbrite [PDF]
, 2016 Joints are conduits for groundwater, hydrocarbons and hydrothermal fluids. Robust fluid flow models rely on accurate characterisation of joint networks, in particular joint density.
Lunn, R.J., Shipton, Z.K., Soden, A.M.
core +1 more source
Spectroscopic Evidence of Edge‐Localized States in an Antiferromagnet Topological Insulator NdBi
Advanced Science, EarlyView.Using spin‐polarized scanning tunneling microscopy (STM) in conjunction with quasiparticle interference, we successfully identify distinct signatures of the ferromagnetic and antiferromagnetic terminations in NdBi, a rare‐earth monopnictide exhibiting non‐trivial topology and magnetism. We demonstrate that step edges on ferromagnetic surfaces host well‐
Avior Almoalem +8 more
wiley +1 more source
Underground SpaceWhen tunnel boring machines (TBMs) excavate through jointed rock masses, the cutting efficiency is strongly affected by the shear strength of joints, the mechanism of which, however, remains poorly understood.
Bolong Liu +6 more
doaj +1 more source
Advanced Science, EarlyView.Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong +24 more
wiley +1 more source