Results 91 to 100 of about 257,564 (287)

Flash Assembloids: A Rapid Biofabrication of a Platform for Modeling Early Glioblastoma Invasion at the Glioblastoma–Brain Organoid Interfaces

Advanced Healthcare Materials, EarlyView.
This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang, Henry Robert Howard, Shihui Chen, Won‐Young Choi, Summer Cao, Arthur Chien, Kevin Zou, Michael Kassiou, Fabien Delerue, Ho Sang Jung, Yeonju Park, Young Mee Jung, Yong‐Dae Kwon, Karrie M. Kiang, Gilberto Ka‐Kit Leung, Ryohichi Sugimura, Ann‐Na Cho, Sang Jin Lee   +17 more
wiley   +1 more source

Introduction to Selected Contributions from the 54th US Rock Mechanics/Geomechanics Symposium, Golden, CO, 2020. [PDF]

Rock Mech Rock Eng, 2022
Walton G, Hedayat A.
europepmc   +1 more source

ETV2 Mediated Differentiation of Human Pluripotent Stem Cells Results in Functional Endothelial Cells for Engineering Advanced Vascularized Microphysiological Models

Advanced Healthcare Materials, EarlyView.
A robust method to generate functional human iPSC‐derived endothelial cells using inducible ETV2 expression. These cells self‐organize into stable, lumenized microvascular networks within microfluidic chips, surpassing conventional differentiation methods.
Shun Zhang, Zhengpeng Wan, Lei Wang, Caihong Wu, Junkai Zhang, Sarah Spitz, Xun Wang, Marie A. Floryan, Mark F. Coughlin, Francesca M. Pramotton, Liling Xu, Ron Weiss, Roger D. Kamm   +12 more
wiley   +1 more source

A General Framework to Simulate Soil–Structure Interface Behaviour Using Advanced Constitutive Models

Modelling
The importance of using sophisticated interface models to obtain realistic numerical solutions of soil–structure interaction (SSI) problems has been recognised in recent decades. With this aim, various advanced interface models have been developed, which
Michael Niebler, Stylianos Chrisopoulos, Roberto Cudmani, Daniel Rebstock   +3 more
doaj   +1 more source

Complex Networks on a Rock Joint

, 2009
A complex network approach on a rough fracture is developed. In this manner, some hidden metric spaces (similarity measurements) between apertures profiles are set up and a general evolutionary network in two directions (in parallel and perpendicular to ...
Evgin, E., Fall, M., Ghaffari, H. O., Sharifzadeh, M.   +3 more
core  

A Long‐Lived Human Neurovascular PENTA Culture Model Captures Incomplete Vascular Repair and Glia‐Associated Signaling After Traumatic Brain Injury

Advanced Healthcare Materials, EarlyView.
A long‐lived, five‐cell‐type human neurovascular (PENTA) model recreates vascular disorganization and incomplete repair after traumatic brain injury (TBI). By integrating endothelial, glial, neuronal, and immune components within a 3D scaffold, the platform enables time‐resolved analysis of neurovascular remodeling and provides a human‐relevant system ...
Daniel S. Hinrichsen, Sunghyun Jun, Colleen M. Arrasmith, Charitha C. Anamala, Mitchell D. Thielen, Anapaula Garcia, Volha Liaudanskaya   +6 more
wiley   +1 more source

EXPANSION OF A CYLINDRICAL CAVITY IN SAND

TASK Quarterly, 2000
The paper presents numerical solution to the problem of the symmetric quasi-static large-strain expansion of a cylindrical cavity in sand. The boundary value problem is solved with the use of a constitutive equation of hypoplasticity calibrated for a ...
VOLODIA A. OSINOV, ROBERTO CUDMANI
doaj  

Development of a Synthetic Hydrogel to Foster Microvascularization of an Endometriosis Microphysiological System

Advanced Healthcare Materials, EarlyView.
ABSTRACT The ascent of novel alternative methods in drug development spotlights the dual needs for improved biological fidelity to in vivo, along with reproducibility, especially in regulatory applications. The need for pre‐clinical models of patient‐derived endometriosis lesions motivates the development of a vascularizable, completely synthetic ...
Lauren Pruett, Laura Bahlmann, Ryan Ogi, Angela Jiao, Priyatanu Roy, Matthew Johnson, David Trumper, Linda Griffith   +7 more
wiley   +1 more source

CALCULATION OF SOIL DISPLACEMENTS DUE TO RETAINING WALL CONSTRUCTION

TASK Quarterly, 2000
With regard to serviceability state deformations, diaphragm walls and slurry walls cause considerable soil deformations during trench construction. 3-dimensional finite element analyses are able to quantify these deformations.
PETER KUDELLA, PETER M. MAYER
doaj  

AI-assisted reliability-based design framework for tunnel concrete linings in weak rocks

Scientific Reports
Reliability-based design (RBD) of tunnel concrete linings in weak rocks is challenging due to the uncertainty of geomechanical parameters and the ground–support interaction.
Jafar Khani, Hamid Reza Nejati, Kamran Goshtasbi, Sina Rostamabadi, Arsalan Mahmoodzadeh   +4 more
doaj   +1 more source