Results 31 to 40 of about 1,360,571 (249)

Research on Rock Strength Test Based on Electro-Hydraulic Servo Point Load Instrument

open access: yesApplied Sciences, 2022
A new electro-hydraulic servo point load instrument was designed to address the problem that the existing point load instrument cannot be loaded continuously and uniformly; different loading rates (using three loading rates: 0.1, 0.5, 1.0 kN/s) were ...
Xiaoxia Zhou   +5 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

A new empirical approach for prediction of rock mass strength based on a strength reducing curve zone instead of unique strength reducing curve [PDF]

open access: yes, 2010
ISRM International Symposium - 6th Asian Rock Mechanics Symposium: Advances in Rock Engineering, ARMS 2010 -- 23 October 2010 through 27 October 2010 -- New Delhi -- 139012As is well known from rock mechanics literature, the mechanical parameters of a ...
Sonmez, Harun   +4 more
core   +1 more source

Heterogeneity Measures for Analyzing the Scale Effect and Anisotropy of Joint Roughness

open access: yesJournal of Mathematics
Joint roughness of rock joints is one of the key factors influencing the mechanical properties of rock joints. The influence of joint roughness on the mechanical properties of rock mass is usually quantitatively characterized by joint roughness ...
Jibo Qin, Zhenhan Zhang, Jun Ye
doaj   +1 more source

Effect of multiple loading rates on uniaxial compressive strength of rock

open access: yes, 2022
It is of crucial significance to study the effect of loading rate on the behaviour of rock because engineering structures are subjected to multiple loading conditions in their entire life. Although rock behaviour under single loading rate has been widely
Meerza, J., Khandelwal, Manoj
core  

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Numerical modeling of strain transfer from rock mass to a fibre optic sensor installed inside a grouted borehole [PDF]

open access: yes, 2012
, 2023Strain measurements in underground excavation are usually done locally, with extensometers or similar devices placed within 10-15 meters of adit or stope faces, mainly to gage development of the EDZ (excavation damaged zone) and assess its ...
Dusseault, M.B.   +3 more
core   +1 more source

A Practical Noise2Noise Denoising Pipeline for High‐Throughput Raman Spectroscopy

open access: yesAdvanced Engineering Materials, EarlyView.
A lightweight and reproducible denoising pipeline for high‐throughput Raman spectroscopy is introduced, based on a 1D convolutional autoencoder trained with a Noise2Noise strategy. Using only repeated short‐exposure acquisitions, the method suppresses stochastic noise without reference spectra, enabling reliable spectral reconstruction while preserving
David Martin‐Calle   +5 more
wiley   +1 more source

Rock Mechanics Through Project-Based Learning

open access: yes, 2019
Traditional textbooks on rock mechanics often fail to engage students in the learning process as such books are packed with theory that students are unlikely to use in their future employment.
Gratchev, Ivan
core   +1 more source

Leveraging Symbolic Artificial Intelligence and Fuzzy Logic for Materials Science: A Review of Methods, Challenges, and Applications to Scarce and Imperfect Experimental Data

open access: yesAdvanced Engineering Materials, EarlyView.
This article explores the transformative potential of symbolic artificial intelligence (AI) in the field of materials science, particularly in leveraging experimental data. The article presents several symbolic AI models and discusses their applications in materials science.
Ahmed Amrani   +7 more
wiley   +1 more source

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