Results 41 to 50 of about 257,564 (287)
Mechanical properties of granulite from Horní Bory in Bohemian massif [PDF]
, 2019 Granulite represents one of the favourite rock types for the construction of an underground nuclear waste repository in the Czech Republic. Granulite from the Bohemian Massif (locality Horní Bory) was investigated in this study, with a special focus ...
Blümel, Manfred +4 more
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Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Heterogeneity Measures for Analyzing the Scale Effect and Anisotropy of Joint Roughness
Journal of MathematicsJoint roughness of rock joints is one of the key factors influencing the mechanical properties of rock joints. The influence of joint roughness on the mechanical properties of rock mass is usually quantitatively characterized by joint roughness ...
Jibo Qin, Zhenhan Zhang, Jun Ye
doaj +1 more source
Quasi-static stationary-periodic model of percussive deep drilling [PDF]
, 2005 Copyright @ 2005 Patron EditoreIn the percussively deep drilling, the rock is modeled by an infinite elastic medium with a semi-infinite cylindrical bore-hole having a curvilinear bottom.
Mikhailov, SE, Namestnikova, IV
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A fractal fragmentation model for rockfalls [PDF]
, 2017 The final publication is available at Springer via http://dx.doi.org/10.1007/s10346-016-0773-8The impact-induced rock mass fragmentation in a rockfall is analyzed by comparing the in situ block size distribution (IBSD) of the rock mass detached from the ...
Corominas Dulcet, Jordi +2 more
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Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Criteria for rapid sliding I.: a review of Vaiont case [PDF]
, 2010 Vaiont slide has been represented by a model of two interacting evolutive wedges. Mass conservation during the motion implies that the upper wedge transfers mass to the lower one through an internal shearing plane.
Alonso Pérez de Agreda, Eduardo +1 more
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Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
State-of-the-art review on plant-based solutions for soil improvement
Biogeotechnics, 2023 Vegetation has been used as a means in geotechnical engineering for soil improvement and erosion control. This paper aims to present a state-of-the-art review and future prospective on soil improvement and reinforcement with plants, mainly from a ...
Shanshan Li +2 more
doaj +1 more source
Дослідження впливу зенітного кута на стійкість стінок стовбурів, що знаходяться в пружно-деформованому стані в процесі буріння горизонтальних свердловин [PDF]
, 2011 Розглядається проблема стійкості стінок стовбура свердловини в процесі буріння, що супроводжується осипанням та обвалюванням породи в нестійких продуктивних горизонтах та прихопленням породоруйнівного інструменту, з точки зору пружно-деформованого стану ...
Кунцяк, Я. В. +1 more
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