Results 51 to 60 of about 257,564 (287)

Dynamic development of hydrofracture [PDF]

open access: yes, 2013
Many natural examples of complex joint and vein networks in layered sedimentary rocks are hydrofractures that form by a combination of pore fluid overpressure and tectonic stresses.
Ghani, Irfan   +3 more
core   +6 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Determination of stability of epimetamorphic rock slope using Minimax Probability Machine

open access: yesGeomatics, Natural Hazards & Risk, 2016
The article employs Minimax Probability Machine (MPM) for the prediction of the stability status of epimetamorphic rock slope. The MPM gives a worst-case bound on the probability of misclassification of future data points.
Manoj Kumar   +2 more
doaj   +1 more source

Experimental Study on Mesoscopic Shear Behavior of Calcareous Sand Material with Digital Imaging Approach

open access: yesAdvances in Civil Engineering, 2020
The study of the mesostructure of soil under loading is the basis for understanding its macromechanical properties and for establishing its constitutive model.
Jianhua Shen   +5 more
doaj   +1 more source

Physical modeling of the rock bolt interaction with the rock massif [PDF]

open access: yesE3S Web of Conferences, 2019
The results of the physical modeling of the “rock bolt – rock massif” system are presented. The characteristics of rock bolt free oscillations depending on the degree of its clamping and tension were studied on special test benches.
Skipochka Serhii   +3 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Research on charge induction law and application of coal samples with different fissures

open access: yesScientific Reports, 2023
Indoor testing are performed to explore the charge induction law during the uniaxial compression fracture process of coal samples, and the charge time and frequency domain signals of coal samples with different primary fissures are analyzed in the paper.
Gang Wang   +5 more
doaj   +1 more source

Elastic Behavior of Transversely Isotropic Cylindrical Rock Samples under Uniaxial Compression Considering Ideal and Frictional Boundary Conditions

open access: yesApplied Sciences, 2023
Conceptualizing sophisticated measurement set-ups as well as testing and evaluation procedures for laboratory experiments on anisotropic rocks requires a basic understanding of the potential specimen behavior.
Manuel Bernhard Winkler   +2 more
doaj   +1 more source

Phase field modelling of crack propagation, branching and coalescence in rocks

open access: yes, 2018
We present a phase field model (PFM) for simulating complex crack patterns including crack propagation, branching and coalescence in rock. The phase field model is implemented in COMSOL and is based on the strain decomposition for the elastic energy ...
Rabczuk, Timon   +3 more
core   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

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